Acquired resistance to interferon alpha therapy associated with homozygous MPL-W515L mutation and chromosome 20q deletion in primary myelofibrosis

MeSH terms

• Chromosome Deletion*
• Chromosomes, Human, Pair 20*
• Drug Resistance, Neoplasm*
• Homozygote*
• Humans
• Interferon-alpha / therapeutic use*
• Male
• Middle Aged
• Mutation*
• Primary Myelofibrosis / drug therapy*
• Primary Myelofibrosis / genetics