Abstract
We detected distinct plasma concentration profiles of S100B, neuropeptide Y, and secretagogin in 3 of 191 patients enrolled in a previous study investigating brain-tissue-related markers in the blood of patients with atrial fibrillation. Intriguingly, 2 of these 3 patients, both of whom were without neurological symptoms at the time of blood sampling, were diagnosed with malignant glioma (MG) approximately 1 year later. To our knowledge, this is the first report indicating that distinct blood biomarker profiles may be detected long before clinical manifestation of MG.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Atrial Fibrillation / blood
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Biomarkers, Tumor / blood*
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Brain Neoplasms / blood*
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Calcium-Binding Proteins / blood*
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Female
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Glioma / blood*
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Humans
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Male
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Middle Aged
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Nerve Growth Factors / blood*
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Neuropeptide Y / blood*
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S100 Calcium Binding Protein beta Subunit
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S100 Proteins / blood*
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Secretagogins
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Young Adult
Substances
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Biomarkers, Tumor
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Calcium-Binding Proteins
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Nerve Growth Factors
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Neuropeptide Y
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S100 Calcium Binding Protein beta Subunit
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S100 Proteins
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S100B protein, human
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SCGN protein, human
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Secretagogins