Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery

MeSH terms

• Anti-Bacterial Agents / pharmacology*
• Anti-Bacterial Agents / therapeutic use
• Bacterial Proteins / genetics
• Bacterial Proteins / physiology*
• Drug Discovery
• Drug Resistance, Bacterial*
• Gene Knockout Techniques
• Gram-Negative Bacteria / drug effects*
• Gram-Negative Bacteria / genetics
• Gram-Positive Bacterial Infections / drug therapy*
• Haemophilus influenzae / drug effects
• Haemophilus influenzae / genetics
• Humans
• Microbial Sensitivity Tests
• Multidrug Resistance-Associated Proteins / genetics
• Multidrug Resistance-Associated Proteins / physiology*