Abstract
The fastest and the brightest: A new design that intimately connects tetrazine to a BODIPY fluorophore enables exceptionally efficient energy transfer and quenching. Upon reaction of the tetrazine, the brightness of the fluorophore increases more than a thousand-fold, a fluorogenic activation up to two orders of magnitude greater than previously described.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Boron Compounds / chemical synthesis
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Boron Compounds / chemistry*
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Click Chemistry
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Fluorescent Dyes
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Molecular Structure
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Spectrometry, Fluorescence / methods
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Tetrazoles / chemistry*
Substances
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4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
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Boron Compounds
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Fluorescent Dyes
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Tetrazoles