Pharmacologic and surgical interventions to improve functional capacity in heart failure

Antonio Abbate; Benjamin W Van Tassell; Justin M Canada; Dave L Dixon; Ross A Arena; Giuseppe Biondi-Zoccai

doi:10.1016/j.hfc.2014.08.005

Pharmacologic and surgical interventions to improve functional capacity in heart failure

Heart Fail Clin. 2015 Jan;11(1):117-24. doi: 10.1016/j.hfc.2014.08.005. Epub 2014 Oct 3.

Authors

Antonio Abbate¹, Benjamin W Van Tassell², Justin M Canada³, Dave L Dixon², Ross A Arena⁴, Giuseppe Biondi-Zoccai⁵

Affiliations

¹ VCU Pauley Heart Center, Virginia Commonwealth University, 1200 East Broad Street, Box 980281, Richmond, VA 23298, USA. Electronic address: aabbate@vcu.edu.
² School of Pharmacy, Virginia Commonwealth University, 410 North 12th Street, Box 980533, Richmond, VA 23298, USA.
³ Department of Kinesiology and Health Sciences, College of Humanities and Sciences, Virginia Commonwealth University, 1200 East Marshall Street, Box 980419, Richmond, VA 23298, USA.
⁴ Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, 1919 West Taylor Street, 454 AHSB, Chicago, IL 60612, USA.
⁵ Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Corso della Repubblica 79, Latina 04100, Italy.

PMID: 25432480
DOI: 10.1016/j.hfc.2014.08.005

Abstract

Heart failure (HF) is a clinical syndrome of breathlessness, lower extremity swelling, fatigue, and exercise intolerance affecting a large portion of the population worldwide, and associated with premature death. Despite improvement in the management of HF, many patients remain unable to complete activities of daily living without experiencing exertional symptoms. Although prevention of death in patients with HF is imperative, treatment of symptoms and improving functional capacity are equally important goals. This article discusses treatments (medical and surgical) associated with improved functional capacity in HF.

Keywords: Device; Drugs; Functional capacity; Heart failure; Surgery; Treatments.

Publication types

Review

MeSH terms

Activities of Daily Living*
Cardiac Surgical Procedures / methods*
Cardiotonic Agents / pharmacology*
Exercise Test
Heart Failure* / drug therapy
Heart Failure* / physiopathology
Heart Failure* / surgery
Humans
Ventricular Function / physiology*

Substances

Cardiotonic Agents