We aimed to examine the relationship between total dairy and dairy subtypes with the risk of type 2 diabetes (T2DM) in an Asian population. A nested case-control study of 178 cases of incident T2DM and 520 matched controls was conducted within the Tehran lipid and glucose study (TLGS). A 27% lower risk of T2DM was found per 100 g/d total dairy consumption that tend to be significant (95% CI: 0.52-1.02). Milk intake was inversely associated with diabetes after adjustment for confounders (p-trend: 0.042). Milk intake was associated with decreased T2DM risk in men (p-trend: 0.025), but not in women (p-trend: 0.527). Each 100 g/d increase in milk intake corresponded to 41% lower T2DM risk in fully adjusted model (95% CI: 0.39-0.89) in men. In conclusion, there is no significant association between diabetes and total dairy intake in the present study, but high intake of milk may reduce T2DM risk among men.
Keywords: Dairy products; Tehran lipid and glucose study; nested case–control study; preventative nutrition and chronic disease; type 2 diabetes.