Differentiation of subtypes of renal cell carcinoma: dynamic contrast-enhanced magnetic resonance imaging versus diffusion-weighted magnetic resonance imaging

Clin Imaging. 2017 Jan-Feb:41:53-58. doi: 10.1016/j.clinimag.2016.10.001. Epub 2016 Oct 7.

Abstract

Objective: The objective was to compare the performance of dynamic contrast-enhanced (DCE) and diffusion-weighted (DW) magnetic resonance (MR) imaging in the differentiation of subtypes of renal cell carcinoma (RCC).

Materials/methods: This study included 45 renal tumors of clear cell (n=36) and non-clear-cell (n=9) RCC. The contrast enhancement ratios (CERs) and the apparent diffusion coefficient (ADC) values on MR imaging were compared between the clear cell and non-clear-cell RCC groups.

Results: In the comparison of diagnostic performance between DCE and DW MR imaging, areas under the curves were 0.968 and 0.797 for the CERs of the corticomedullary and the ADC value.

Conclusion: The CER of the corticomedullary phase was more reliable in distinguishing between clear cell and non-clear-cell RCCs.

Keywords: Contrast-enhanced imaging; Diffusion-weighted imaging; Renal cell carcinoma; Subtype.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Renal Cell / diagnostic imaging*
  • Carcinoma, Renal Cell / pathology
  • Contrast Media*
  • Diagnosis, Differential
  • Diffusion Magnetic Resonance Imaging / methods
  • Female
  • Humans
  • Image Enhancement / methods*
  • Kidney Neoplasms / diagnostic imaging*
  • Kidney Neoplasms / pathology
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Young Adult

Substances

  • Contrast Media