Life with the pancreas: A personal experience

Adv Med Sci. 2020 Mar;65(1):46-64. doi: 10.1016/j.advms.2019.11.002. Epub 2019 Dec 31.

Abstract

This review article has primary objective to summarize pancreatic research which has been done in our laboratory since 1965, the first year of the author's registration in the Ph.D. program at the University of Sherbrooke (Canada). It covers the following major topics of pancreatic physiology: controls of pancreatic adaptation to diet, control of pancreatic enzyme secretion, control of pancreatic enzyme synthesis, control of pancreatic growth, intracellular events stimulated during pancreatic growth, pancreas regeneration after pancreatitis and pancreatectomy, the pancreatic cholecystokinin receptor types 1 and 2, growth control and cell signaling in pancreatic cancer cells and finally, cystic fibrosis.

Keywords: Enzyme synthesis and growth; Pancreatic secretion.

Publication types

  • Review

MeSH terms

  • Animals
  • Cystic Fibrosis / physiopathology*
  • Cystic Fibrosis / therapy
  • Humans
  • Pancreas / physiology*
  • Pancreatic Neoplasms / physiopathology*
  • Pancreatic Neoplasms / therapy
  • Pancreatitis / physiopathology*
  • Pancreatitis / therapy
  • Regeneration*