Novel EWSR1-VGLL1 fusion in a pediatric neuroepithelial neoplasm

Clin Genet. 2020 May;97(5):791-792. doi: 10.1111/cge.13703. Epub 2020 Jan 16.

Authors

Adam J Kundishora¹, Benjamin C Reeves¹, Carol Nelson-Williams², Christopher S Hong¹, Pallavi P Gopal³, Matija Snuderl⁴, Kristopher T Kahle^{1

5

6}, E Zeynep Erson-Omay¹

Affiliations

¹ Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut.
² Department of Genetics, Yale School of Medicine, New Haven, Connecticut.
³ Department of Pathology, Yale School of Medicine, New Haven, Connecticut.
⁴ Department of Pathology, NYU Langone Health, New York, New York.
⁵ Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
⁶ Department of Cellular & Molecular Physiology, NIH Yale-Rockefeller Centers for Mendelian Genomics, New Haven, Connecticut.

PMID: 31925773
DOI: 10.1111/cge.13703

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Child
DNA-Binding Proteins / genetics*
Female
Genetic Predisposition to Disease
Humans
Male
Neoplasms, Neuroepithelial / genetics*
Neoplasms, Neuroepithelial / pathology
Oncogene Proteins, Fusion / genetics*
Oncogene Proteins, Fusion / isolation & purification
Pediatrics
RNA-Binding Protein EWS / genetics*
Transcription Factors / genetics*

Substances

DNA-Binding Proteins
EWSR1 protein, human
Oncogene Proteins, Fusion
RNA-Binding Protein EWS
Transcription Factors
VGLL1 protein, human

Grants and funding

K12 NS080223/NS/NINDS NIH HHS/United States