The implication of 'unknown significance' variants in next-generation sequencing in diagnosis and donor selection for allogenic haematopoietic stem cell transplantation. Report of a case of myelodysplastic syndrome with a polymorphism in the tyrosine kinase 2 (TYK2) gene

Br J Haematol. 2020 May;189(4):e182-e184. doi: 10.1111/bjh.16590. Epub 2020 Apr 8.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Hematopoietic Stem Cell Transplantation / methods*
  • High-Throughput Nucleotide Sequencing / methods
  • Humans
  • Male
  • Myelodysplastic Syndromes / genetics*
  • Myelodysplastic Syndromes / therapy*
  • Polymorphism, Genetic
  • TYK2 Kinase / genetics*
  • Transplantation Conditioning / methods*
  • Transplantation, Homologous

Substances

  • TYK2 Kinase