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Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.
Leibman RS, Richardson MW, Ellebrecht CT, Maldini CR, Glover JA, Secreto AJ, Kulikovskaya I, Lacey SF, Akkina SR, Yi Y, Shaheen F, Wang J, Dufendach KA, Holmes MC, Collman RG, Payne AS, Riley JL. Leibman RS, et al. Among authors: shaheen f. PLoS Pathog. 2017 Oct 12;13(10):e1006613. doi: 10.1371/journal.ppat.1006613. eCollection 2017 Oct. PLoS Pathog. 2017. PMID: 29023549 Free PMC article.
Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV.
Tebas P, Stein D, Binder-Scholl G, Mukherjee R, Brady T, Rebello T, Humeau L, Kalos M, Papasavvas E, Montaner LJ, Schullery D, Shaheen F, Brennan AL, Zheng Z, Cotte J, Slepushkin V, Veloso E, Mackley A, Hwang WT, Aberra F, Zhan J, Boyer J, Collman RG, Bushman FD, Levine BL, June CH. Tebas P, et al. Among authors: shaheen f. Blood. 2013 Feb 28;121(9):1524-33. doi: 10.1182/blood-2012-07-447250. Epub 2012 Dec 20. Blood. 2013. PMID: 23264589 Free PMC article. Clinical Trial.
Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected].
Graf EH, Pace MJ, Peterson BA, Lynch LJ, Chukwulebe SB, Mexas AM, Shaheen F, Martin JN, Deeks SG, Connors M, Migueles SA, O'Doherty U. Graf EH, et al. Among authors: shaheen f. PLoS One. 2013 Aug 7;8(8):e71879. doi: 10.1371/journal.pone.0071879. eCollection 2013. PLoS One. 2013. PMID: 23951263 Free PMC article.
Co-receptor antagonists as HIV-1 entry inhibitors.
Shaheen F, Collman RG. Shaheen F, et al. Curr Opin Infect Dis. 2004 Feb;17(1):7-16. doi: 10.1097/00001432-200402000-00003. Curr Opin Infect Dis. 2004. PMID: 15090884 Review.
Dualtropic CXCR6/CCR5 Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabey Primary Lymphocytes: Distinct Coreceptor Use in Natural versus Pathogenic Hosts of SIV.
Elliott ST, Wetzel KS, Francella N, Bryan S, Romero DC, Riddick NE, Shaheen F, Vanderford T, Derdeyn CA, Silvestri G, Paiardini M, Collman RG. Elliott ST, et al. Among authors: shaheen f. J Virol. 2015 Sep;89(18):9252-61. doi: 10.1128/JVI.01236-15. Epub 2015 Jun 24. J Virol. 2015. PMID: 26109719 Free PMC article.
Combination genetic therapy to inhibit HIV-1.
Strayer DS, Branco F, Landré J, BouHamdan M, Shaheen F, Pomerantz RJ. Strayer DS, et al. Among authors: shaheen f. Mol Ther. 2002 Jan;5(1):33-41. doi: 10.1006/mthe.2001.0513. Mol Ther. 2002. PMID: 11786043 Free article.
486 results