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Phase I trial of the cyclin-dependent kinase inhibitor and protein kinase C inhibitor 7-hydroxystaurosporine in combination with Fluorouracil in patients with advanced solid tumors.
Kortmansky J, Shah MA, Kaubisch A, Weyerbacher A, Yi S, Tong W, Sowers R, Gonen M, O'reilly E, Kemeny N, Ilson DI, Saltz LB, Maki RG, Kelsen DP, Schwartz GK. Kortmansky J, et al. Among authors: sowers r. J Clin Oncol. 2005 Mar 20;23(9):1875-84. doi: 10.1200/JCO.2005.03.116. Epub 2005 Feb 7. J Clin Oncol. 2005. PMID: 15699481 Clinical Trial.
Decreased levels of UMP kinase as a mechanism of fluoropyrimidine resistance.
Humeniuk R, Menon LG, Mishra PJ, Gorlick R, Sowers R, Rode W, Pizzorno G, Cheng YC, Kemeny N, Bertino JR, Banerjee D. Humeniuk R, et al. Among authors: sowers r. Mol Cancer Ther. 2009 May;8(5):1037-44. doi: 10.1158/1535-7163.MCT-08-0716. Epub 2009 Apr 21. Mol Cancer Ther. 2009. PMID: 19383847
Lack of correlation of functional scintigraphy with (99m)technetium-methoxyisobutylisonitrile with histological necrosis following induction chemotherapy or measures of P-glycoprotein expression in high-grade osteosarcoma.
Gorlick R, Liao AC, Antonescu C, Huvos AG, Healey JH, Sowers R, Daras M, Calleja E, Wexler LH, Panicek D, Meyers PA, Yeh SD, Larson SM. Gorlick R, et al. Among authors: sowers r. Clin Cancer Res. 2001 Oct;7(10):3065-70. Clin Cancer Res. 2001. PMID: 11595696
43 results