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Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome.
Johnson JD, Bernal-Mizrachi E, Alejandro EU, Han Z, Kalynyak TB, Li H, Beith JL, Gross J, Warnock GL, Townsend RR, Permutt MA, Polonsky KS. Johnson JD, et al. Among authors: permutt ma. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19575-80. doi: 10.1073/pnas.0604208103. Epub 2006 Dec 8. Proc Natl Acad Sci U S A. 2006. PMID: 17158802 Free PMC article.
Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion.
Ohsugi M, Cras-Méneur C, Zhou Y, Bernal-Mizrachi E, Johnson JD, Luciani DS, Polonsky KS, Permutt MA. Ohsugi M, et al. Among authors: permutt ma. J Biol Chem. 2005 Feb 11;280(6):4992-5003. doi: 10.1074/jbc.M411727200. Epub 2004 Nov 15. J Biol Chem. 2005. PMID: 15546857 Free article.
Gene expression profiling in islet biology and diabetes research.
Bernal-Mizrachi E, Cras-Méneur C, Ohsugi M, Permutt MA. Bernal-Mizrachi E, et al. Among authors: permutt ma. Diabetes Metab Res Rev. 2003 Jan-Feb;19(1):32-42. doi: 10.1002/dmrr.331. Diabetes Metab Res Rev. 2003. PMID: 12592642 Review.
207 results