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Disrupting Inflammation-Associated CXCL8-CXCR1 Signaling Inhibits Tumorigenicity Initiated by Sporadic- and Colitis-Colon Cancer Stem Cells.
Fisher RC, Bellamkonda K, Alex Molina L, Xiang S, Liska D, Sarvestani SK, Chakrabarti S, Berg A, Jorgensen ML, Hatala D, Chen S, Aiello A, Appelman HD, Scott EW, Huang EH. Fisher RC, et al. Among authors: appelman hd. Neoplasia. 2019 Mar;21(3):269-281. doi: 10.1016/j.neo.2018.12.007. Epub 2019 Feb 7. Neoplasia. 2019. PMID: 30738331 Free PMC article.
Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis.
Chen S, Fisher RC, Signs S, Molina LA, Shenoy AK, Lopez MC, Baker HV, Koomen JM, Chen Y, Gittleman H, Barnholtz-Sloan J, Berg A, Appelman HD, Huang EH. Chen S, et al. Among authors: appelman hd. Oncotarget. 2016 Jun 8;8(31):50476-50488. doi: 10.18632/oncotarget.9919. eCollection 2017 Aug 1. Oncotarget. 2016. PMID: 28881576 Free PMC article.
Identification, isolation and characterization of human LGR5-positive colon adenoma cells.
Dame MK, Attili D, McClintock SD, Dedhia PH, Ouillette P, Hardt O, Chin AM, Xue X, Laliberte J, Katz EL, Newsome GM, Hill DR, Miller AJ, Tsai YH, Agorku D, Altheim CH, Bosio A, Simon B, Samuelson LC, Stoerker JA, Appelman HD, Varani J, Wicha MS, Brenner DE, Shah YM, Spence JR, Colacino JA. Dame MK, et al. Among authors: appelman hd. Development. 2018 Mar 14;145(6):dev153049. doi: 10.1242/dev.153049. Development. 2018. PMID: 29467240 Free PMC article.
215 results