Zhang T - Search Results

1

Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.

Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, Fields JZ, Wicha MS, Boman BM. Huang EH, et al. Among authors: zhang t. Cancer Res. 2009 Apr 15;69(8):3382-9. doi: 10.1158/0008-5472.CAN-08-4418. Epub 2009 Mar 31. Cancer Res. 2009. PMID: 19336570 Free PMC article.

2

Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells.

Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, Yu Y, Clouthier SG, Schwartz SJ, Wicha MS, Sun D. Li Y, et al. Among authors: zhang t. Clin Cancer Res. 2010 May 1;16(9):2580-90. doi: 10.1158/1078-0432.CCR-09-2937. Epub 2010 Apr 13. Clin Cancer Res. 2010. PMID: 20388854 Free PMC article.

3

An miRNA Expression Signature for the Human Colonic Stem Cell Niche Distinguishes Malignant from Normal Epithelia.

Viswanathan V, Damle S, Zhang T, Opdenaker L, Modarai S, Accerbi M, Schmidt S, Green P, Galileo D, Palazzo J, Fields J, Haghighat S, Rigoutsos I, Gonye G, Boman BM. Viswanathan V, et al. Among authors: zhang t. Cancer Res. 2017 Jul 15;77(14):3778-3790. doi: 10.1158/0008-5472.CAN-16-2388. Epub 2017 May 9. Cancer Res. 2017. PMID: 28487386

4

Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer.

Zhang T, Otevrel T, Gao Z, Gao Z, Ehrlich SM, Fields JZ, Boman BM. Zhang T, et al. Cancer Res. 2001 Dec 15;61(24):8664-7. Cancer Res. 2001. PMID: 11751382

5

One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis.

Yeung AT, Patel BB, Li XM, Seeholzer SH, Coudry RA, Cooper HS, Bellacosa A, Boman BM, Zhang T, Litwin S, Ross EA, Conrad P, Crowell JA, Kopelovich L, Knudson A. Yeung AT, et al. Among authors: zhang t. Cancer Res. 2008 Sep 15;68(18):7579-86. doi: 10.1158/0008-5472.CAN-08-0856. Cancer Res. 2008. PMID: 18794146 Free PMC article.

6

APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development.

Zhang T, Ahn K, Emerick B, Modarai SR, Opdenaker LM, Palazzo J, Schleiniger G, Fields JZ, Boman BM. Zhang T, et al. PLoS One. 2020 Oct 28;15(10):e0239601. doi: 10.1371/journal.pone.0239601. eCollection 2020. PLoS One. 2020. PMID: 33112876 Free PMC article.

7

Increased Musashi-2 and Decreased NUMB Protein Levels Observed in Human Colorectal Cancer are reverted to Normal Levels by ATRA-Induced Cell Differentiation.

Opdenaker LM, Kowash R, Masters G, Boman BM, Zhang T, Modarai SR. Opdenaker LM, et al. Among authors: zhang t. Int J Cancer Res Ther. 2018;3(2):10.33140/ijcrt/03/02/00003. doi: 10.33140/ijcrt/03/02/00003. Epub 2018 Aug 15. Int J Cancer Res Ther. 2018. PMID: 32984754 Free PMC article.

8

Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population.

Boman BM, Walters R, Fields JZ, Kovatich AJ, Zhang T, Isenberg GA, Goldstein SD, Palazzo JP. Boman BM, et al. Among authors: zhang t. Am J Pathol. 2004 Nov;165(5):1489-98. doi: 10.1016/S0002-9440(10)63407-4. Am J Pathol. 2004. PMID: 15509520 Free PMC article.

9

Survivin-induced Aurora-B kinase activation: A mechanism by which APC mutations contribute to increased mitoses during colon cancer development.

Zhang T, Fields JZ, Opdenaker L, Otevrel T, Masuda E, Palazzo JP, Isenberg GA, Goldstein SD, Brand M, Boman BM. Zhang T, et al. Am J Pathol. 2010 Dec;177(6):2816-26. doi: 10.2353/ajpath.2010.100047. Epub 2010 Nov 5. Am J Pathol. 2010. PMID: 21057000 Free PMC article.

10

The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cells.

Modarai SR, Gupta A, Opdenaker LM, Kowash R, Masters G, Viswanathan V, Zhang T, Fields JZ, Boman BM. Modarai SR, et al. Among authors: zhang t. Oncotarget. 2018 Oct 5;9(78):34658-34669. doi: 10.18632/oncotarget.26157. eCollection 2018 Oct 5. Oncotarget. 2018. PMID: 30410666 Free PMC article.

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