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Page 1
Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation.
Boudreau LH, Duchez AC, Cloutier N, Soulet D, Martin N, Bollinger J, Paré A, Rousseau M, Naika GS, Lévesque T, Laflamme C, Marcoux G, Lambeau G, Farndale RW, Pouliot M, Hamzeh-Cognasse H, Cognasse F, Garraud O, Nigrovic PA, Guderley H, Lacroix S, Thibault L, Semple JW, Gelb MH, Boilard E. Boudreau LH, et al. Among authors: farndale rw. Blood. 2014 Oct 2;124(14):2173-83. doi: 10.1182/blood-2014-05-573543. Epub 2014 Jul 31. Blood. 2014. PMID: 25082876 Free PMC article.
Platelets can enhance vascular permeability.
Cloutier N, Paré A, Farndale RW, Schumacher HR, Nigrovic PA, Lacroix S, Boilard E. Cloutier N, et al. Among authors: farndale rw. Blood. 2012 Aug 9;120(6):1334-43. doi: 10.1182/blood-2012-02-413047. Epub 2012 Apr 27. Blood. 2012. PMID: 22544703 Free article.
The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes.
Cloutier N, Tan S, Boudreau LH, Cramb C, Subbaiah R, Lahey L, Albert A, Shnayder R, Gobezie R, Nigrovic PA, Farndale RW, Robinson WH, Brisson A, Lee DM, Boilard E. Cloutier N, et al. Among authors: farndale rw. EMBO Mol Med. 2013 Feb;5(2):235-49. doi: 10.1002/emmm.201201846. Epub 2012 Dec 11. EMBO Mol Med. 2013. PMID: 23165896 Free PMC article.
Collagen-induced platelet activation.
Farndale RW. Farndale RW. Blood Cells Mol Dis. 2006 Mar-Apr;36(2):162-5. doi: 10.1016/j.bcmd.2005.12.016. Epub 2006 Feb 7. Blood Cells Mol Dis. 2006. PMID: 16464621 Review.
Structural basis for collagen recognition by the immune receptor OSCAR.
Zhou L, Hinerman JM, Blaszczyk M, Miller JL, Conrady DG, Barrow AD, Chirgadze DY, Bihan D, Farndale RW, Herr AB. Zhou L, et al. Among authors: farndale rw. Blood. 2016 Feb 4;127(5):529-37. doi: 10.1182/blood-2015-08-667055. Epub 2015 Nov 9. Blood. 2016. PMID: 26552697 Free PMC article.
Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood.
Jung SM, Moroi M, Soejima K, Nakagaki T, Miura Y, Berndt MC, Gardiner EE, Howes JM, Pugh N, Bihan D, Watson SP, Farndale RW. Jung SM, et al. Among authors: farndale rw. J Biol Chem. 2012 Aug 24;287(35):30000-13. doi: 10.1074/jbc.M112.359125. Epub 2012 Jul 6. J Biol Chem. 2012. PMID: 22773837 Free PMC article. Clinical Trial.
228 results