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The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Alemán JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR. Taniguchi CM, et al. Among authors: winnay j. Cancer Res. 2010 Jul 1;70(13):5305-15. doi: 10.1158/0008-5472.CAN-09-3399. Epub 2010 Jun 8. Cancer Res. 2010. PMID: 20530665 Free PMC article.
PI 3-kinase regulatory subunits as regulators of the unfolded protein response.
Winnay JN, Kahn CR. Winnay JN, et al. Methods Enzymol. 2011;490:147-58. doi: 10.1016/B978-0-12-385114-7.00009-X. Methods Enzymol. 2011. PMID: 21266249 Free PMC article.
Recently, we and Park et al. have characterized a novel function for the p85alpha and p85beta subunits as modulators of the UPR by virtue of their ability to facilitate the nuclear entry of XBP-1s following induction of ER stress (Park, S. W., Zhou, Y., Lee, J., Lu, A., Su …
Recently, we and Park et al. have characterized a novel function for the p85alpha and p85beta subunits as modulators of the UPR by virtue of …
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.
Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR. Tseng YH, et al. Among authors: winnay jn. Nature. 2008 Aug 21;454(7207):1000-4. doi: 10.1038/nature07221. Nature. 2008. PMID: 18719589 Free PMC article.
36 results