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MMP-13 selective isonipecotamide alpha-sulfone hydroxamates.
Kolodziej SA, Hockerman SL, DeCrescenzo GA, McDonald JJ, Mischke DA, Munie GE, Fletcher TR, Stehle N, Swearingen C, Becker DP. Kolodziej SA, et al. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3561-4. doi: 10.1016/j.bmcl.2010.04.111. Epub 2010 Apr 28. Bioorg Med Chem Lett. 2010. PMID: 20529685
Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metrics.
Lau WF, Withka JM, Hepworth D, Magee TV, Du YJ, Bakken GA, Miller MD, Hendsch ZS, Thanabal V, Kolodziej SA, Xing L, Hu Q, Narasimhan LS, Love R, Charlton ME, Hughes S, van Hoorn WP, Mills JE. Lau WF, et al. Among authors: kolodziej sa. J Comput Aided Mol Des. 2011 Jul;25(7):621-36. doi: 10.1007/s10822-011-9434-0. Epub 2011 May 21. J Comput Aided Mol Des. 2011. PMID: 21604056
Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1).
Tremont SJ, Lee LF, Huang HC, Keller BT, Banerjee SC, Both SR, Carpenter AJ, Wang CC, Garland DJ, Huang W, Jones C, Koeller KJ, Kolodziej SA, Li J, Manning RE, Mahoney MW, Miller RE, Mischke DA, Rath NP, Fletcher T, Reinhard EJ, Tollefson MB, Vernier WF, Wagner GM, Rapp SR, Beaudry J, Glenn K, Regina K, Schuh JR, Smith ME, Trivedi JS, Reitz DB. Tremont SJ, et al. Among authors: kolodziej sa. J Med Chem. 2005 Sep 8;48(18):5837-52. doi: 10.1021/jm040215+. J Med Chem. 2005. PMID: 16134950
Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 2).
Huang HC, Tremont SJ, Lee LF, Keller BT, Carpenter AJ, Wang CC, Banerjee SC, Both SR, Fletcher T, Garland DJ, Huang W, Jones C, Koeller KJ, Kolodziej SA, Li J, Manning RE, Mahoney MW, Miller RE, Mischke DA, Rath NP, Reinhard EJ, Tollefson MB, Vernier WF, Wagner GM, Rapp SR, Beaudry J, Glenn K, Regina K, Schuh JR, Smith ME, Trivedi JS, Reitz DB. Huang HC, et al. Among authors: kolodziej sa. J Med Chem. 2005 Sep 8;48(18):5853-68. doi: 10.1021/jm0402162. J Med Chem. 2005. PMID: 16134951
23 results