Longo VD - Search Results

1

Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans.

Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, Wei M, Madia F, Cheng CW, Hwang D, Martin-Montalvo A, Saavedra J, Ingles S, de Cabo R, Cohen P, Longo VD. Guevara-Aguirre J, et al. Among authors: longo vd. Sci Transl Med. 2011 Feb 16;3(70):70ra13. doi: 10.1126/scitranslmed.3001845. Sci Transl Med. 2011. PMID: 21325617 Free PMC article.

2

A simple model system for age-dependent DNA damage and cancer.

Madia F, Gattazzo C, Fabrizio P, Longo VD. Madia F, et al. Among authors: longo vd. Mech Ageing Dev. 2007 Jan;128(1):45-9. doi: 10.1016/j.mad.2006.11.009. Epub 2006 Nov 21. Mech Ageing Dev. 2007. PMID: 17118426 Free PMC article. Review.

3

Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system.

Madia F, Gattazzo C, Wei M, Fabrizio P, Burhans WC, Weinberger M, Galbani A, Smith JR, Nguyen C, Huey S, Comai L, Longo VD. Madia F, et al. Among authors: longo vd. J Cell Biol. 2008 Jan 14;180(1):67-81. doi: 10.1083/jcb.200707154. J Cell Biol. 2008. PMID: 18195102 Free PMC article.

4

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9.

Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L, Longo VD. Wei M, et al. Among authors: longo vd. PLoS Genet. 2008 Jan;4(1):e13. doi: 10.1371/journal.pgen.0040013. Epub 2007 Dec 13. PLoS Genet. 2008. PMID: 18225956 Free PMC article.

5

Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.

Raffaghello L, Lee C, Safdie FM, Wei M, Madia F, Bianchi G, Longo VD. Raffaghello L, et al. Among authors: longo vd. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8215-20. doi: 10.1073/pnas.0708100105. Epub 2008 Mar 31. Proc Natl Acad Sci U S A. 2008. PMID: 18378900 Free PMC article.

6

Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension.

Wei M, Fabrizio P, Madia F, Hu J, Ge H, Li LM, Longo VD. Wei M, et al. Among authors: longo vd. PLoS Genet. 2009 May;5(5):e1000467. doi: 10.1371/journal.pgen.1000467. Epub 2009 May 8. PLoS Genet. 2009. PMID: 19424415 Free PMC article.

7

Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Polzeta-dependent mechanism.

Madia F, Wei M, Yuan V, Hu J, Gattazzo C, Pham P, Goodman MF, Longo VD. Madia F, et al. Among authors: longo vd. J Cell Biol. 2009 Aug 24;186(4):509-23. doi: 10.1083/jcb.200906011. Epub 2009 Aug 17. J Cell Biol. 2009. PMID: 19687253 Free PMC article.

8

Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index.

Lee C, Safdie FM, Raffaghello L, Wei M, Madia F, Parrella E, Hwang D, Cohen P, Bianchi G, Longo VD. Lee C, et al. Among authors: longo vd. Cancer Res. 2010 Feb 15;70(4):1564-72. doi: 10.1158/0008-5472.CAN-09-3228. Epub 2010 Feb 9. Cancer Res. 2010. PMID: 20145127 Free PMC article.

9

Fasting and cancer treatment in humans: A case series report.

Safdie FM, Dorff T, Quinn D, Fontana L, Wei M, Lee C, Cohen P, Longo VD. Safdie FM, et al. Among authors: longo vd. Aging (Albany NY). 2009 Dec 31;1(12):988-1007. doi: 10.18632/aging.100114. Aging (Albany NY). 2009. PMID: 20157582 Free PMC article.

10

Linking Klotho, Nrf2, MAP kinases and aging.

Balasubramanian P, Longo VD. Balasubramanian P, et al. Among authors: longo vd. Aging (Albany NY). 2010 Oct;2(10):632-3. doi: 10.18632/aging.100219. Aging (Albany NY). 2010. PMID: 21076180 Free PMC article. No abstract available.

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