Baker BF - Search Results

1

Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial.

Visser ME, Wagener G, Baker BF, Geary RS, Donovan JM, Beuers UH, Nederveen AJ, Verheij J, Trip MD, Basart DC, Kastelein JJ, Stroes ES. Visser ME, et al. Among authors: baker bf. Eur Heart J. 2012 May;33(9):1142-9. doi: 10.1093/eurheartj/ehs023. Epub 2012 Apr 16. Eur Heart J. 2012. PMID: 22507979 Free PMC article. Clinical Trial.

2

A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis.

van Deventer SJ, Wedel MK, Baker BF, Xia S, Chuang E, Miner PB Jr. van Deventer SJ, et al. Among authors: baker bf. Aliment Pharmacol Ther. 2006 May 15;23(10):1415-25. doi: 10.1111/j.1365-2036.2006.02910.x. Aliment Pharmacol Ther. 2006. PMID: 16669956 Free article. Clinical Trial.

3

Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.

Kastelein JJ, Wedel MK, Baker BF, Su J, Bradley JD, Yu RZ, Chuang E, Graham MJ, Crooke RM. Kastelein JJ, et al. Among authors: baker bf. Circulation. 2006 Oct 17;114(16):1729-35. doi: 10.1161/CIRCULATIONAHA.105.606442. Epub 2006 Oct 9. Circulation. 2006. PMID: 17030687 Clinical Trial.

4

Efficacy and safety of mipomersen, an antisense inhibitor of apolipoprotein B, in hypercholesterolemic subjects receiving stable statin therapy.

Akdim F, Stroes ES, Sijbrands EJ, Tribble DL, Trip MD, Jukema JW, Flaim JD, Su J, Yu R, Baker BF, Wedel MK, Kastelein JJ. Akdim F, et al. Among authors: baker bf. J Am Coll Cardiol. 2010 Apr 13;55(15):1611-8. doi: 10.1016/j.jacc.2009.11.069. J Am Coll Cardiol. 2010. PMID: 20378080 Free article. Clinical Trial.

5

Effect of mipomersen, an apolipoprotein B synthesis inhibitor, on low-density lipoprotein cholesterol in patients with familial hypercholesterolemia.

Akdim F, Visser ME, Tribble DL, Baker BF, Stroes ES, Yu R, Flaim JD, Su J, Stein EA, Kastelein JJ. Akdim F, et al. Among authors: baker bf. Am J Cardiol. 2010 May 15;105(10):1413-9. doi: 10.1016/j.amjcard.2010.01.003. Epub 2010 Mar 30. Am J Cardiol. 2010. PMID: 20451687 Clinical Trial.

6

Efficacy of apolipoprotein B synthesis inhibition in subjects with mild-to-moderate hyperlipidaemia.

Akdim F, Tribble DL, Flaim JD, Yu R, Su J, Geary RS, Baker BF, Fuhr R, Wedel MK, Kastelein JJ. Akdim F, et al. Among authors: baker bf. Eur Heart J. 2011 Nov;32(21):2650-9. doi: 10.1093/eurheartj/ehr148. Epub 2011 May 18. Eur Heart J. 2011. PMID: 21593041 Clinical Trial.

7

Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans.

Graham MJ, Lee RG, Bell TA 3rd, Fu W, Mullick AE, Alexander VJ, Singleton W, Viney N, Geary R, Su J, Baker BF, Burkey J, Crooke ST, Crooke RM. Graham MJ, et al. Among authors: baker bf. Circ Res. 2013 May 24;112(11):1479-90. doi: 10.1161/CIRCRESAHA.111.300367. Epub 2013 Mar 29. Circ Res. 2013. PMID: 23542898 Clinical Trial.

8

Changes in mipomersen dosing regimen provide similar exposure with improved tolerability in randomized placebo-controlled study of healthy volunteers.

Flaim JD, Grundy JS, Baker BF, McGowan MP, Kastelein JJ. Flaim JD, et al. Among authors: baker bf. J Am Heart Assoc. 2014 Mar 13;3(2):e000560. doi: 10.1161/JAHA.113.000560. J Am Heart Assoc. 2014. PMID: 24627419 Free PMC article. Clinical Trial.

9

Effects of an antisense oligonucleotide inhibitor of C-reactive protein synthesis on the endotoxin challenge response in healthy human male volunteers.

Noveck R, Stroes ES, Flaim JD, Baker BF, Hughes S, Graham MJ, Crooke RM, Ridker PM. Noveck R, et al. Among authors: baker bf. J Am Heart Assoc. 2014 Jul 10;3(4):e001084. doi: 10.1161/JAHA.114.001084. J Am Heart Assoc. 2014. PMID: 25012289 Free PMC article. Clinical Trial.

10

Targeting APOC3 in the familial chylomicronemia syndrome.

Gaudet D, Brisson D, Tremblay K, Alexander VJ, Singleton W, Hughes SG, Geary RS, Baker BF, Graham MJ, Crooke RM, Witztum JL. Gaudet D, et al. Among authors: baker bf. N Engl J Med. 2014 Dec 4;371(23):2200-6. doi: 10.1056/NEJMoa1400284. N Engl J Med. 2014. PMID: 25470695 Free article.

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