Kaestner KH - Search Results

1

Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human islets.

Rieck S, Zhang J, Li Z, Liu C, Naji A, Takane KK, Fiaschi-Taesch NM, Stewart AF, Kushner JA, Kaestner KH. Rieck S, et al. Among authors: kaestner kh. Mol Endocrinol. 2012 Sep;26(9):1590-602. doi: 10.1210/me.2012-1019. Epub 2012 Jul 13. Mol Endocrinol. 2012. PMID: 22798294 Free PMC article.

2

Transcriptional networks in the liver: hepatocyte nuclear factor 6 function is largely independent of Foxa2.

Rubins NE, Friedman JR, Le PP, Zhang L, Brestelli J, Kaestner KH. Rubins NE, et al. Among authors: kaestner kh. Mol Cell Biol. 2005 Aug;25(16):7069-77. doi: 10.1128/MCB.25.16.7069-7077.2005. Mol Cell Biol. 2005. PMID: 16055718 Free PMC article.

3

Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation.

Vatamaniuk MZ, Gupta RK, Lantz KA, Doliba NM, Matschinsky FM, Kaestner KH. Vatamaniuk MZ, et al. Among authors: kaestner kh. Diabetes. 2006 Oct;55(10):2730-6. doi: 10.2337/db05-0470. Diabetes. 2006. PMID: 17003337

4

Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.

Hardy OT, Hohmeier HE, Becker TC, Manduchi E, Doliba NM, Gupta RK, White P, Stoeckert CJ Jr, Matschinsky FM, Newgard CB, Kaestner KH. Hardy OT, et al. Among authors: kaestner kh. Mol Endocrinol. 2007 Mar;21(3):765-73. doi: 10.1210/me.2006-0411. Epub 2006 Dec 21. Mol Endocrinol. 2007. PMID: 17185391

5

Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha.

Gupta RK, Gao N, Gorski RK, White P, Hardy OT, Rafiq K, Brestelli JE, Chen G, Stoeckert CJ Jr, Kaestner KH. Gupta RK, et al. Among authors: kaestner kh. Genes Dev. 2007 Apr 1;21(7):756-69. doi: 10.1101/gad.1535507. Genes Dev. 2007. PMID: 17403778 Free PMC article.

6

Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development.

Tan X, Yuan Y, Zeng G, Apte U, Thompson MD, Cieply B, Stolz DB, Michalopoulos GK, Kaestner KH, Monga SP. Tan X, et al. Among authors: kaestner kh. Hepatology. 2008 May;47(5):1667-79. doi: 10.1002/hep.22225. Hepatology. 2008. PMID: 18393386 Free PMC article.

7

Foxl1 is a marker of bipotential hepatic progenitor cells in mice.

Sackett SD, Li Z, Hurtt R, Gao Y, Wells RG, Brondell K, Kaestner KH, Greenbaum LE. Sackett SD, et al. Among authors: kaestner kh. Hepatology. 2009 Mar;49(3):920-9. doi: 10.1002/hep.22705. Hepatology. 2009. PMID: 19105206 Free PMC article.

8

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH. Gao N, et al. Among authors: kaestner kh. Genes Dev. 2008 Dec 15;22(24):3435-48. doi: 10.1101/gad.1752608. Genes Dev. 2008. PMID: 19141476 Free PMC article.

9

Foxa1 and Foxa2 regulate bile duct development in mice.

Li Z, White P, Tuteja G, Rubins N, Sackett S, Kaestner KH. Li Z, et al. Among authors: kaestner kh. J Clin Invest. 2009 Jun;119(6):1537-45. doi: 10.1172/JCI38201. Epub 2009 May 11. J Clin Invest. 2009. PMID: 19436110 Free PMC article.

10

The transcriptional response of the islet to pregnancy in mice.

Rieck S, White P, Schug J, Fox AJ, Smirnova O, Gao N, Gupta RK, Wang ZV, Scherer PE, Keller MP, Attie AD, Kaestner KH. Rieck S, et al. Among authors: kaestner kh. Mol Endocrinol. 2009 Oct;23(10):1702-12. doi: 10.1210/me.2009-0144. Epub 2009 Jul 2. Mol Endocrinol. 2009. PMID: 19574445 Free PMC article.

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