Kushner JA - Search Results

1

Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human islets.

Rieck S, Zhang J, Li Z, Liu C, Naji A, Takane KK, Fiaschi-Taesch NM, Stewart AF, Kushner JA, Kaestner KH. Rieck S, et al. Among authors: kushner ja. Mol Endocrinol. 2012 Sep;26(9):1590-602. doi: 10.1210/me.2012-1019. Epub 2012 Jul 13. Mol Endocrinol. 2012. PMID: 22798294 Free PMC article.

2

Calcineurin signaling regulates human islet {beta}-cell survival.

Soleimanpour SA, Crutchlow MF, Ferrari AM, Raum JC, Groff DN, Rankin MM, Liu C, De León DD, Naji A, Kushner JA, Stoffers DA. Soleimanpour SA, et al. Among authors: kushner ja. J Biol Chem. 2010 Dec 17;285(51):40050-9. doi: 10.1074/jbc.M110.154955. Epub 2010 Oct 13. J Biol Chem. 2010. PMID: 20943662 Free PMC article.

3

Cyclin D2 protein stability is regulated in pancreatic beta-cells.

He LM, Sartori DJ, Teta M, Opare-Addo LM, Rankin MM, Long SY, Diehl JA, Kushner JA. He LM, et al. Among authors: kushner ja. Mol Endocrinol. 2009 Nov;23(11):1865-75. doi: 10.1210/me.2009-0057. Epub 2009 Jul 23. Mol Endocrinol. 2009. PMID: 19628581 Free PMC article.

4

GATA factors promote ER integrity and β-cell survival and contribute to type 1 diabetes risk.

Sartori DJ, Wilbur CJ, Long SY, Rankin MM, Li C, Bradfield JP, Hakonarson H, Grant SF, Pu WT, Kushner JA. Sartori DJ, et al. Among authors: kushner ja. Mol Endocrinol. 2014 Jan;28(1):28-39. doi: 10.1210/me.2013-1265. Epub 2013 Jan 1. Mol Endocrinol. 2014. PMID: 24284823 Free PMC article.

5

Aging induces a distinct gene expression program in mouse islets.

Rankin MM, Kushner JA. Rankin MM, et al. Among authors: kushner ja. Islets. 2010 Nov-Dec;2(6):345-52. doi: 10.4161/isl.2.6.13376. Epub 2010 Nov 1. Islets. 2010. PMID: 21099336 Free PMC article.

6

β Cells Persist in T1D Pancreata Without Evidence of Ongoing β-Cell Turnover or Neogenesis.

Lam CJ, Jacobson DR, Rankin MM, Cox AR, Kushner JA. Lam CJ, et al. Among authors: kushner ja. J Clin Endocrinol Metab. 2017 Aug 1;102(8):2647-2659. doi: 10.1210/jc.2016-3806. J Clin Endocrinol Metab. 2017. PMID: 28323930 Free PMC article.

7

Incretin Therapies Do Not Expand β-Cell Mass or Alter Pancreatic Histology in Young Male Mice.

Cox AR, Lam CJ, Rankin MM, Rios JS, Chavez J, Bonnyman CW, King KB, Wells RA, Anthony D, Tu JX, Kim JJ, Li C, Kushner JA. Cox AR, et al. Among authors: kushner ja. Endocrinology. 2017 Jun 1;158(6):1701-1714. doi: 10.1210/en.2017-00027. Endocrinology. 2017. PMID: 28323942 Free PMC article.

8

Adaptive beta-cell proliferation is severely restricted with advanced age.

Rankin MM, Kushner JA. Rankin MM, et al. Among authors: kushner ja. Diabetes. 2009 Jun;58(6):1365-72. doi: 10.2337/db08-1198. Epub 2009 Mar 5. Diabetes. 2009. PMID: 19265026 Free PMC article.

9

miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner.

Chitnis NS, Pytel D, Bobrovnikova-Marjon E, Pant D, Zheng H, Maas NL, Frederick B, Kushner JA, Chodosh LA, Koumenis C, Fuchs SY, Diehl JA. Chitnis NS, et al. Among authors: kushner ja. Mol Cell. 2012 Nov 9;48(3):353-64. doi: 10.1016/j.molcel.2012.08.025. Epub 2012 Sep 27. Mol Cell. 2012. PMID: 23022383 Free PMC article.

10

PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.

Gao Y, Sartori DJ, Li C, Yu QC, Kushner JA, Simon MC, Diehl JA. Gao Y, et al. Among authors: kushner ja. Mol Cell Biol. 2012 Dec;32(24):5129-39. doi: 10.1128/MCB.01009-12. Epub 2012 Oct 15. Mol Cell Biol. 2012. PMID: 23071091 Free PMC article.

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