Zhang J - Search Results

1

Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human islets.

Rieck S, Zhang J, Li Z, Liu C, Naji A, Takane KK, Fiaschi-Taesch NM, Stewart AF, Kushner JA, Kaestner KH. Rieck S, et al. Among authors: zhang j. Mol Endocrinol. 2012 Sep;26(9):1590-602. doi: 10.1210/me.2012-1019. Epub 2012 Jul 13. Mol Endocrinol. 2012. PMID: 22798294 Free PMC article.

2

Epigenetic Analysis of Endocrine Cell Subtypes from Human Pancreatic Islets.

Zhang J, Kaestner KH. Zhang J, et al. Methods Mol Biol. 2017;1507:95-111. doi: 10.1007/978-1-4939-6518-2_8. Methods Mol Biol. 2017. PMID: 27832535

3

The diabetes gene Hhex maintains δ-cell differentiation and islet function.

Zhang J, McKenna LB, Bogue CW, Kaestner KH. Zhang J, et al. Genes Dev. 2014 Apr 15;28(8):829-34. doi: 10.1101/gad.235499.113. Genes Dev. 2014. PMID: 24736842 Free PMC article.

4

High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting.

Ackermann AM, Zhang J, Heller A, Briker A, Kaestner KH. Ackermann AM, et al. Among authors: zhang j. Mol Metab. 2017 Jan 12;6(3):236-244. doi: 10.1016/j.molmet.2017.01.003. eCollection 2017 Mar. Mol Metab. 2017. PMID: 28271030 Free PMC article.

5

Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice.

Ou K, Zhang J, Jiao Y, Wang ZV, Scherer P, Kaestner KH. Ou K, et al. Among authors: zhang j. Mol Metab. 2018 May;11:212-217. doi: 10.1016/j.molmet.2018.03.009. Epub 2018 Mar 23. Mol Metab. 2018. PMID: 29650351 Free PMC article.

6

The Dysregulation of the DLK1-MEG3 Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE-DNMT Constructs.

Kameswaran V, Golson ML, Ramos-Rodríguez M, Ou K, Wang YJ, Zhang J, Pasquali L, Kaestner KH. Kameswaran V, et al. Among authors: zhang j. Diabetes. 2018 Sep;67(9):1807-1815. doi: 10.2337/db17-0682. Epub 2018 Jul 3. Diabetes. 2018. PMID: 30084829 Free PMC article.

7

Targeting the cell cycle inhibitor p57Kip2 promotes adult human β cell replication.

Avrahami D, Li C, Yu M, Jiao Y, Zhang J, Naji A, Ziaie S, Glaser B, Kaestner KH. Avrahami D, et al. Among authors: zhang j. J Clin Invest. 2014 Feb;124(2):670-4. doi: 10.1172/JCI69519. Epub 2014 Jan 16. J Clin Invest. 2014. PMID: 24430183 Free PMC article.

8

Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function.

Avrahami D, Li C, Zhang J, Schug J, Avrahami R, Rao S, Stadler MB, Burger L, Schübeler D, Glaser B, Kaestner KH. Avrahami D, et al. Among authors: zhang j. Cell Metab. 2015 Oct 6;22(4):619-32. doi: 10.1016/j.cmet.2015.07.025. Epub 2015 Aug 27. Cell Metab. 2015. PMID: 26321660 Free PMC article.

9

Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice.

Ferreira MJ, McKenna LB, Zhang J, Reichert M, Bakir B, Buza EL, Furth EE, Bogue CW, Rustgi AK, Kaestner KH. Ferreira MJ, et al. Among authors: zhang j. Cell Mol Gastroenterol Hepatol. 2015 Sep 1;1(5):550-569. doi: 10.1016/j.jcmgh.2015.06.007. Cell Mol Gastroenterol Hepatol. 2015. PMID: 26740970 Free PMC article.

10

PAX6 maintains β cell identity by repressing genes of alternative islet cell types.

Swisa A, Avrahami D, Eden N, Zhang J, Feleke E, Dahan T, Cohen-Tayar Y, Stolovich-Rain M, Kaestner KH, Glaser B, Ashery-Padan R, Dor Y. Swisa A, et al. Among authors: zhang j. J Clin Invest. 2017 Jan 3;127(1):230-243. doi: 10.1172/JCI88015. Epub 2016 Dec 12. J Clin Invest. 2017. PMID: 27941241 Free PMC article.

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