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Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.
Muili KA, Wang D, Orabi AI, Sarwar S, Luo Y, Javed TA, Eisses JF, Mahmood SM, Jin S, Singh VP, Ananthanaravanan M, Perides G, Williams JA, Molkentin JD, Husain SZ. Muili KA, et al. Among authors: perides g. J Biol Chem. 2013 Jan 4;288(1):570-80. doi: 10.1074/jbc.M112.428896. Epub 2012 Nov 12. J Biol Chem. 2013. PMID: 23148215 Free PMC article.
Ryanodine receptors contribute to bile acid-induced pathological calcium signaling and pancreatitis in mice.
Husain SZ, Orabi AI, Muili KA, Luo Y, Sarwar S, Mahmood SM, Wang D, Choo-Wing R, Singh VP, Parness J, Ananthanaravanan M, Bhandari V, Perides G. Husain SZ, et al. Among authors: perides g. Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15;302(12):G1423-33. doi: 10.1152/ajpgi.00546.2011. Epub 2012 Apr 19. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22517774 Free PMC article.
Protease-activated receptor-2 exerts contrasting model-specific effects on acute experimental pancreatitis.
Laukkarinen JM, Weiss ER, van Acker GJ, Steer ML, Perides G. Laukkarinen JM, et al. Among authors: perides g. J Biol Chem. 2008 Jul 25;283(30):20703-12. doi: 10.1074/jbc.M801779200. Epub 2008 May 28. J Biol Chem. 2008. PMID: 18511423 Free PMC article.
Protease-activated receptor-2 (PAR2) is a 7-transmembrane G-protein-coupled tethered ligand receptor that is expressed by pancreatic acinar and ductal cells. ...L., and Perides, G. (2005) Am. J. Physiol. 288, G388-G395) have shown that PAR2 activation exerts …
Protease-activated receptor-2 (PAR2) is a 7-transmembrane G-protein-coupled tethered ligand receptor that is expressed by pancreatic …
88 results