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CD47 fusion protein targets CD172a+ cells in Crohn's disease and dampens the production of IL-1β and TNF.
Baba N, Van VQ, Wakahara K, Rubio M, Fortin G, Panzini B, Soucy G, Wassef R, Richard C, Tamaz R, Lahaie R, Bernard EJ, Caussignac Y, Leduc R, Lougnarath R, Bergeron C, Racicot MA, Bergeron F, Panzini MA, Demetter P, Franchimont D, Schäkel K, Weckbecker G, Kolbinger F, Heusser C, Huber T, Welzenbach K, Sarfati M. Baba N, et al. Among authors: welzenbach k. J Exp Med. 2013 Jun 3;210(6):1251-63. doi: 10.1084/jem.20122037. Epub 2013 May 13. J Exp Med. 2013. PMID: 23669395 Free PMC article.
Pharmacodynamics in the development of new immunosuppressive drugs.
Burkhart C, Heusser C, Morris RE, Raulf F, Weckbecker G, Weitz-Schmidt G, Welzenbach K. Burkhart C, et al. Among authors: welzenbach k. Ther Drug Monit. 2004 Dec;26(6):588-92. doi: 10.1097/00007691-200412000-00002. Ther Drug Monit. 2004. PMID: 15570181 Review.
1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1.
Wattanasin S, Kallen J, Myers S, Guo Q, Sabio M, Ehrhardt C, Albert R, Hommel U, Weckbecker G, Welzenbach K, Weitz-Schmidt G. Wattanasin S, et al. Among authors: welzenbach k. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1217-20. doi: 10.1016/j.bmcl.2004.11.072. Bioorg Med Chem Lett. 2005. PMID: 15686945
The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation.
Evenou JP, Wagner J, Zenke G, Brinkmann V, Wagner K, Kovarik J, Welzenbach KA, Weitz-Schmidt G, Guntermann C, Towbin H, Cottens S, Kaminski S, Letschka T, Lutz-Nicoladoni C, Gruber T, Hermann-Kleiter N, Thuille N, Baier G. Evenou JP, et al. Among authors: welzenbach ka. J Pharmacol Exp Ther. 2009 Sep;330(3):792-801. doi: 10.1124/jpet.109.153205. Epub 2009 Jun 2. J Pharmacol Exp Ther. 2009. PMID: 19491325
20 results