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Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.
Hayes HL, Moss LG, Schisler JC, Haldeman JM, Zhang Z, Rosenberg PB, Newgard CB, Hohmeier HE. Hayes HL, et al. Among authors: schisler jc. Mol Cell Biol. 2013 Oct;33(20):4017-29. doi: 10.1128/MCB.00469-13. Epub 2013 Aug 12. Mol Cell Biol. 2013. PMID: 23938296 Free PMC article.
Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes.
Iype T, Francis J, Garmey JC, Schisler JC, Nesher R, Weir GC, Becker TC, Newgard CB, Griffen SC, Mirmira RG. Iype T, et al. Among authors: schisler jc. J Biol Chem. 2005 Apr 29;280(17):16798-807. doi: 10.1074/jbc.M414381200. Epub 2005 Mar 2. J Biol Chem. 2005. PMID: 15743769 Free article.
MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet.
He J, Quintana MT, Sullivan J, L Parry T, J Grevengoed T, Schisler JC, Hill JA, Yates CC, Mapanga RF, Essop MF, Stansfield WE, Bain JR, Newgard CB, Muehlbauer MJ, Han Y, Clarke BA, Willis MS. He J, et al. Among authors: schisler jc. Cardiovasc Diabetol. 2015 Aug 5;14:97. doi: 10.1186/s12933-015-0252-x. Cardiovasc Diabetol. 2015. PMID: 26242235 Free PMC article.
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