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Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Wang S, Tsun ZY, Wolfson RL, Shen K, Wyant GA, Plovanich ME, Yuan ED, Jones TD, Chantranupong L, Comb W, Wang T, Bar-Peled L, Zoncu R, Straub C, Kim C, Park J, Sabatini BL, Sabatini DM. Wang S, et al. Among authors: tsun zy. Science. 2015 Jan 9;347(6218):188-94. doi: 10.1126/science.1257132. Epub 2015 Jan 7. Science. 2015. PMID: 25567906 Free PMC article.
Amino acid management in cancer.
Tsun ZY, Possemato R. Tsun ZY, et al. Semin Cell Dev Biol. 2015 Jul;43:22-32. doi: 10.1016/j.semcdb.2015.08.002. Epub 2015 Aug 12. Semin Cell Dev Biol. 2015. PMID: 26277542 Free PMC article. Review.
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM. Possemato R, et al. Among authors: tsun zy. Nature. 2011 Aug 18;476(7360):346-50. doi: 10.1038/nature10350. Nature. 2011. PMID: 21760589 Free PMC article.
A histone demethylase is necessary for regeneration in zebrafish.
Stewart S, Tsun ZY, Izpisua Belmonte JC. Stewart S, et al. Among authors: tsun zy. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19889-94. doi: 10.1073/pnas.0904132106. Epub 2009 Nov 6. Proc Natl Acad Sci U S A. 2009. PMID: 19897725 Free PMC article.