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Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.
J Med Chem. 2013 Dec 12;56(23):9701-8. doi: 10.1021/jm401382v. Epub 2013 Nov 21.
J Med Chem. 2013.
PMID: 24215368
Effect of coadministration of moxifloxacin and rifampin on Mycobacterium tuberculosis in a murine aerosol infection model.
Balasubramanian V, Solapure S, Gaonkar S, Mahesh Kumar KN, Shandil RK, Deshpande A, Kumar N, Vishwas KG, Panduga V, Reddy J, Ganguly S, Louie A, Drusano GL.
Balasubramanian V, et al. Among authors: vishwas kg.
Antimicrob Agents Chemother. 2012 Jun;56(6):3054-7. doi: 10.1128/AAC.06383-11. Epub 2012 Apr 2.
Antimicrob Agents Chemother. 2012.
PMID: 22470118
Free PMC article.
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In vitro and in vivo efficacy of β-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis.
Solapure S, Dinesh N, Shandil R, Ramachandran V, Sharma S, Bhattacharjee D, Ganguly S, Reddy J, Ahuja V, Panduga V, Parab M, Vishwas KG, Kumar N, Balganesh M, Balasubramanian V.
Solapure S, et al. Among authors: vishwas kg.
Antimicrob Agents Chemother. 2013 Jun;57(6):2506-10. doi: 10.1128/AAC.00023-13. Epub 2013 Mar 18.
Antimicrob Agents Chemother. 2013.
PMID: 23507276
Free PMC article.
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Pharmacokinetics and dose response of anti-TB drugs in rat infection model of tuberculosis.
Kumar N, Vishwas KG, Kumar M, Reddy J, Parab M, Manikanth CL, Pavithra BS, Shandil RK.
Kumar N, et al. Among authors: vishwas kg.
Tuberculosis (Edinb). 2014 May;94(3):282-6. doi: 10.1016/j.tube.2014.02.004. Epub 2014 Feb 21.
Tuberculosis (Edinb). 2014.
PMID: 24629633
Free article.
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The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo.
Boldrin F, Ventura M, Degiacomi G, Ravishankar S, Sala C, Svetlikova Z, Ambady A, Dhar N, Kordulakova J, Zhang M, Serafini A, Vishwas KG, Kolly GS, Kumar N, Palù G, Guerin ME, Mikusova K, Cole ST, Manganelli R.
Boldrin F, et al. Among authors: vishwas kg.
J Bacteriol. 2014 Oct;196(19):3441-51. doi: 10.1128/JB.01346-13. Epub 2014 Jul 21.
J Bacteriol. 2014.
PMID: 25049093
Free PMC article.
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