Sun J - Search Results

1

Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes.

Guo H, Xiong Y, Witkowski P, Cui J, Wang LJ, Sun J, Lara-Lemus R, Haataja L, Hutchison K, Shan SO, Arvan P, Liu M. Guo H, et al. Among authors: sun j. J Biol Chem. 2014 Jun 6;289(23):16290-302. doi: 10.1074/jbc.M114.562355. Epub 2014 Apr 25. J Biol Chem. 2014. PMID: 24770419 Free PMC article.

2

INS-gene mutations: from genetics and beta cell biology to clinical disease.

Liu M, Sun J, Cui J, Chen W, Guo H, Barbetti F, Arvan P. Liu M, et al. Among authors: sun j. Mol Aspects Med. 2015 Apr;42:3-18. doi: 10.1016/j.mam.2014.12.001. Epub 2014 Dec 24. Mol Aspects Med. 2015. PMID: 25542748 Free PMC article. Review.

3

Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.

Sun J, Cui J, He Q, Chen Z, Arvan P, Liu M. Sun J, et al. Mol Aspects Med. 2015 Apr;42:105-18. doi: 10.1016/j.mam.2015.01.001. Epub 2015 Jan 8. Mol Aspects Med. 2015. PMID: 25579745 Free PMC article. Review.

4

Competitive Inhibition of the Endoplasmic Reticulum Signal Peptidase by Non-cleavable Mutant Preprotein Cargos.

Cui J, Chen W, Sun J, Guo H, Madley R, Xiong Y, Pan X, Wang H, Tai AW, Weiss MA, Arvan P, Liu M. Cui J, et al. Among authors: sun j. J Biol Chem. 2015 Nov 20;290(47):28131-28140. doi: 10.1074/jbc.M115.692350. Epub 2015 Oct 7. J Biol Chem. 2015. PMID: 26446786 Free PMC article.

5

Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins.

Guo H, Sun J, Li X, Xiong Y, Wang H, Shu H, Zhu R, Liu Q, Huang Y, Madley R, Wang Y, Cui J, Arvan P, Liu M. Guo H, et al. Among authors: sun j. J Biol Chem. 2018 Feb 9;293(6):1899-1907. doi: 10.1074/jbc.RA117.000922. Epub 2017 Dec 11. J Biol Chem. 2018. PMID: 29229776 Free PMC article.

6

"Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolution.

Rege NK, Liu M, Dhayalan B, Chen YS, Smith NA, Rahimi L, Sun J, Guo H, Yang Y, Haataja L, Phillips NFB, Whittaker J, Smith BJ, Arvan P, Ismail-Beigi F, Weiss MA. Rege NK, et al. Among authors: sun j. J Biol Chem. 2020 Mar 6;295(10):3080-3098. doi: 10.1074/jbc.RA119.011389. Epub 2020 Jan 31. J Biol Chem. 2020. PMID: 32005662 Free PMC article.

7

Biosynthesis, structure, and folding of the insulin precursor protein.

Liu M, Weiss MA, Arunagiri A, Yong J, Rege N, Sun J, Haataja L, Kaufman RJ, Arvan P. Liu M, et al. Among authors: sun j. Diabetes Obes Metab. 2018 Sep;20 Suppl 2(Suppl 2):28-50. doi: 10.1111/dom.13378. Diabetes Obes Metab. 2018. PMID: 30230185 Free PMC article. Review.

8

Role of Proinsulin Self-Association in Mutant INS Gene-Induced Diabetes of Youth.

Sun J, Xiong Y, Li X, Haataja L, Chen W, Mir SA, Lv L, Madley R, Larkin D, Anjum A, Dhayalan B, Rege N, Wickramasinghe NP, Weiss MA, Itkin-Ansari P, Kaufman RJ, Ostrov DA, Arvan P, Liu M. Sun J, et al. Diabetes. 2020 May;69(5):954-964. doi: 10.2337/db19-1106. Epub 2020 Mar 5. Diabetes. 2020. PMID: 32139596 Free PMC article.

9

Evolution of insulin at the edge of foldability and its medical implications.

Rege NK, Liu M, Yang Y, Dhayalan B, Wickramasinghe NP, Chen YS, Rahimi L, Guo H, Haataja L, Sun J, Ismail-Beigi F, Phillips NB, Arvan P, Weiss MA. Rege NK, et al. Among authors: sun j. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29618-29628. doi: 10.1073/pnas.2010908117. Epub 2020 Nov 5. Proc Natl Acad Sci U S A. 2020. PMID: 33154160 Free PMC article.

10

A Novel Nonsense INS Mutation Causes Inefficient Preproinsulin Translocation Into the Endoplasmic Reticulum.

Yang Y, Shu H, Hu J, Li L, Wang J, Chen T, Zhen J, Sun J, Feng W, Xiong Y, Huang Y, Li X, Zhang K, Fan Z, Guo H, Liu M. Yang Y, et al. Among authors: sun j. Front Endocrinol (Lausanne). 2022 Jan 5;12:774634. doi: 10.3389/fendo.2021.774634. eCollection 2021. Front Endocrinol (Lausanne). 2022. PMID: 35069438 Free PMC article.

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