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ADAM10 regulates Notch function in intestinal stem cells of mice.
Tsai YH, VanDussen KL, Sawey ET, Wade AW, Kasper C, Rakshit S, Bhatt RG, Stoeck A, Maillard I, Crawford HC, Samuelson LC, Dempsey PJ. Tsai YH, et al. Among authors: dempsey pj. Gastroenterology. 2014 Oct;147(4):822-834.e13. doi: 10.1053/j.gastro.2014.07.003. Epub 2014 Jul 16. Gastroenterology. 2014. PMID: 25038433 Free PMC article.
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.
VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, Magness ST, Tran IT, Maillard I, Siebel C, Kolterud Å, Grosse AS, Gumucio DL, Ernst SA, Tsai YH, Dempsey PJ, Samuelson LC. VanDussen KL, et al. Among authors: dempsey pj. Development. 2012 Feb;139(3):488-97. doi: 10.1242/dev.070763. Epub 2011 Dec 21. Development. 2012. PMID: 22190634 Free PMC article.
Rapid Crypt Cell Remodeling Regenerates the Intestinal Stem Cell Niche after Notch Inhibition.
Bohin N, Keeley TM, Carulli AJ, Walker EM, Carlson EA, Gao J, Aifantis I, Siebel CW, Rajala MW, Myers MG Jr, Jones JC, Brindley CD, Dempsey PJ, Samuelson LC. Bohin N, et al. Among authors: dempsey pj. Stem Cell Reports. 2020 Jul 14;15(1):156-170. doi: 10.1016/j.stemcr.2020.05.010. Epub 2020 Jun 11. Stem Cell Reports. 2020. PMID: 32531190 Free PMC article.
ADAM10 as a therapeutic target for cancer and inflammation.
Crawford HC, Dempsey PJ, Brown G, Adam L, Moss ML. Crawford HC, et al. Among authors: dempsey pj. Curr Pharm Des. 2009;15(20):2288-99. doi: 10.2174/138161209788682442. Curr Pharm Des. 2009. PMID: 19601831 Review.
Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.
Dempsey PJ. Dempsey PJ. Biochim Biophys Acta Mol Cell Res. 2017 Nov;1864(11 Pt B):2228-2239. doi: 10.1016/j.bbamcr.2017.07.011. Epub 2017 Jul 22. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28739265 Free PMC article. Review.
178 results