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Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer.
Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Deshpande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes CH, Engelman J, Bardeesy N. Alagesan B, et al. Among authors: hezel af. Clin Cancer Res. 2015 Jan 15;21(2):396-404. doi: 10.1158/1078-0432.CCR-14-1591. Epub 2014 Oct 27. Clin Cancer Res. 2015. PMID: 25348516 Free PMC article.
Telomere induced senescence: end game signaling.
Hezel AF, Bardeesy N, Maser RS. Hezel AF, et al. Curr Mol Med. 2005 Mar;5(2):145-52. doi: 10.2174/1566524053586563. Curr Mol Med. 2005. PMID: 15974867 Review.
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Bardeesy N, et al. Among authors: hezel af. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5947-52. doi: 10.1073/pnas.0601273103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585505 Free PMC article.
Genetics and biology of pancreatic ductal adenocarcinoma.
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA. Hezel AF, et al. Genes Dev. 2006 May 15;20(10):1218-49. doi: 10.1101/gad.1415606. Genes Dev. 2006. PMID: 16702400 Free article. Review.
Stromal biology of pancreatic cancer.
Chu GC, Kimmelman AC, Hezel AF, DePinho RA. Chu GC, et al. Among authors: hezel af. J Cell Biochem. 2007 Jul 1;101(4):887-907. doi: 10.1002/jcb.21209. J Cell Biochem. 2007. PMID: 17266048 Review.
LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis.
Gurumurthy S, Hezel AF, Sahin E, Berger JH, Bosenberg MW, Bardeesy N. Gurumurthy S, et al. Among authors: hezel af. Cancer Res. 2008 Jan 1;68(1):55-63. doi: 10.1158/0008-5472.CAN-07-3225. Cancer Res. 2008. PMID: 18172296 Free PMC article.
76 results