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Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Wang S, Tsun ZY, Wolfson RL, Shen K, Wyant GA, Plovanich ME, Yuan ED, Jones TD, Chantranupong L, Comb W, Wang T, Bar-Peled L, Zoncu R, Straub C, Kim C, Park J, Sabatini BL, Sabatini DM. Wang S, et al. Among authors: comb w. Science. 2015 Jan 9;347(6218):188-94. doi: 10.1126/science.1257132. Epub 2015 Jan 7. Science. 2015. PMID: 25567906 Free PMC article.
Nutrient-sensing mechanisms and pathways.
Efeyan A, Comb WC, Sabatini DM. Efeyan A, et al. Among authors: comb wc. Nature. 2015 Jan 15;517(7534):302-10. doi: 10.1038/nature14190. Nature. 2015. PMID: 25592535 Free PMC article. Review.
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.
Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, Sabatini DM. Shaul YD, et al. Among authors: comb wc. Cell. 2014 Aug 28;158(5):1094-1109. doi: 10.1016/j.cell.2014.07.032. Cell. 2014. PMID: 25171410 Free PMC article.
Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347.
Herscovitch M, Comb W, Ennis T, Coleman K, Yong S, Armstead B, Kalaitzidis D, Chandani S, Gilmore TD. Herscovitch M, et al. Among authors: comb w. Biochem Biophys Res Commun. 2008 Feb 29;367(1):103-8. doi: 10.1016/j.bbrc.2007.12.123. Epub 2007 Dec 28. Biochem Biophys Res Commun. 2008. PMID: 18164680 Free PMC article.
16 results