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Therapeutic neuroprotective agents for amyotrophic lateral sclerosis.
Pandya RS, Zhu H, Li W, Bowser R, Friedlander RM, Wang X. Pandya RS, et al. Among authors: li w. Cell Mol Life Sci. 2013 Dec;70(24):4729-45. doi: 10.1007/s00018-013-1415-0. Epub 2013 Jul 18. Cell Mol Life Sci. 2013. PMID: 23864030 Free PMC article. Review.
N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury.
Zhou H, Wang J, Jiang J, Stavrovskaya IG, Li M, Li W, Wu Q, Zhang X, Luo C, Zhou S, Sirianni AC, Sarkar S, Kristal BS, Friedlander RM, Wang X. Zhou H, et al. Among authors: li w, li m. J Neurosci. 2014 Feb 19;34(8):2967-78. doi: 10.1523/JNEUROSCI.1948-13.2014. J Neurosci. 2014. PMID: 24553937 Free PMC article.
The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity.
Wang X, Sirianni A, Pei Z, Cormier K, Smith K, Jiang J, Zhou S, Wang H, Zhao R, Yano H, Kim JE, Li W, Kristal BS, Ferrante RJ, Friedlander RM. Wang X, et al. Among authors: li w. J Neurosci. 2011 Oct 12;31(41):14496-507. doi: 10.1523/JNEUROSCI.3059-11.2011. J Neurosci. 2011. PMID: 21994366 Free PMC article.
Tartary buckwheat extract alleviates alcohol-induced acute and chronic liver injuries through the inhibition of oxidative stress and mitochondrial cell death pathway.
Yang Q, Luo C, Zhang X, Liu Y, Wang Z, Cacciamani P, Shi J, Cui Y, Wang C, Sinha B, Peng B, Tong G, Das G, Shah E, Gao Y, Li W, Tu Y, Qian D, Shah K, Akbar M, Zhou S, Song BJ, Wang X. Yang Q, et al. Among authors: li w. Am J Transl Res. 2020 Jan 15;12(1):70-89. eCollection 2020. Am J Transl Res. 2020. PMID: 32051738 Free PMC article.
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.
Suofu Y, Li W, Jean-Alphonse FG, Jia J, Khattar NK, Li J, Baranov SV, Leronni D, Mihalik AC, He Y, Cecon E, Wehbi VL, Kim J, Heath BE, Baranova OV, Wang X, Gable MJ, Kretz ES, Di Benedetto G, Lezon TR, Ferrando LM, Larkin TM, Sullivan M, Yablonska S, Wang J, Minnigh MB, Guillaumet G, Suzenet F, Richardson RM, Poloyac SM, Stolz DB, Jockers R, Witt-Enderby PA, Carlisle DL, Vilardaga JP, Friedlander RM. Suofu Y, et al. Among authors: li j, li w. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7997-E8006. doi: 10.1073/pnas.1705768114. Epub 2017 Sep 5. Proc Natl Acad Sci U S A. 2017. PMID: 28874589 Free PMC article.
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