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MafA is a dedicated activator of the insulin gene in vivo.
Artner I, Hang Y, Guo M, Gu G, Stein R. Artner I, et al. Among authors: gu g. J Endocrinol. 2008 Aug;198(2):271-9. doi: 10.1677/JOE-08-0063. Epub 2008 May 30. J Endocrinol. 2008. PMID: 18515495 Free PMC article.
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Conrad E, Dai C, Spaeth J, Guo M, Cyphert HA, Scoville D, Carroll J, Yu WM, Goodrich LV, Harlan DM, Grove KL, Roberts CT Jr, Powers AC, Gu G, Stein R. Conrad E, et al. Among authors: gu g. Am J Physiol Endocrinol Metab. 2016 Jan 1;310(1):E91-E102. doi: 10.1152/ajpendo.00285.2015. Epub 2015 Nov 10. Am J Physiol Endocrinol Metab. 2016. PMID: 26554594 Free PMC article.
Pancreatic Inflammation Redirects Acinar to β Cell Reprogramming.
Clayton HW, Osipovich AB, Stancill JS, Schneider JD, Vianna PG, Shanks CM, Yuan W, Gu G, Manduchi E, Stoeckert CJ Jr, Magnuson MA. Clayton HW, et al. Among authors: gu g. Cell Rep. 2016 Nov 15;17(8):2028-2041. doi: 10.1016/j.celrep.2016.10.068. Cell Rep. 2016. PMID: 27851966 Free PMC article.
Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.
Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ Jr, Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G. Huang C, et al. Among authors: gu g. Dev Cell. 2018 May 7;45(3):347-361.e5. doi: 10.1016/j.devcel.2018.03.013. Epub 2018 Apr 12. Dev Cell. 2018. PMID: 29656931 Free PMC article.
1,935 results