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Page 1
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF, Richter J, Bernhart SH, Efeyan A, Iqbal S, Matthews J, Clear A, Guerra-Assunção JA, Bödör C, Quentmeier H, Mansbridge C, Johnson P, Davies A, Strefford JC, Packham G, Barrans S, Jack A, Du MQ, Calaminici M, Lister TA, Auer R, Montoto S, Gribben JG, Siebert R, Chelala C, Zoncu R, Sabatini DM, Fitzgibbon J. Okosun J, et al. Among authors: escudero ibarz l. Nat Genet. 2016 Feb;48(2):183-8. doi: 10.1038/ng.3473. Epub 2015 Dec 21. Nat Genet. 2016. PMID: 26691987 Free PMC article.
Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Seraihi AF, Richter J, Bernhart SH, Efeyan A, Iqbal S, Matthews J, Clear A, Guerra-Assunção JA, Bödör C, Quentmeier H, Mansbridge C, Johnson P, Davies A, Strefford JC, Packham G, Barrans S, Jack A, Du MQ, Calaminici M, Lister TA, Auer R, Montoto S, Gribben JG, Siebert R, Chelala C, Zoncu R, Sabatini DM, Fitzgibbon J. Okosun J, et al. Among authors: escudero ibarz l. Nat Genet. 2016 May 27;48(6):700. doi: 10.1038/ng0616-700b. Nat Genet. 2016. PMID: 27230687 No abstract available.
Somatic Mutation Screening Using Archival Formalin-Fixed, Paraffin-Embedded Tissues by Fluidigm Multiplex PCR and Illumina Sequencing.
Wang M, Escudero-Ibarz L, Moody S, Zeng N, Clipson A, Huang Y, Xue X, Grigoropoulos NF, Barrans S, Worrillow L, Forshew T, Su J, Firth A, Martin H, Jack A, Brugger K, Du MQ. Wang M, et al. Among authors: escudero ibarz l. J Mol Diagn. 2015 Sep;17(5):521-32. doi: 10.1016/j.jmoldx.2015.04.008. Epub 2015 Jul 9. J Mol Diagn. 2015. PMID: 26165823 Free PMC article.
Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma.
Moody S, Escudero-Ibarz L, Wang M, Clipson A, Ochoa Ruiz E, Dunn-Walters D, Xue X, Zeng N, Robson A, Chuang SS, Cogliatti S, Liu H, Goodlad J, Ashton-Key M, Raderer M, Bi Y, Du MQ. Moody S, et al. Among authors: escudero ibarz l. J Pathol. 2017 Sep;243(1):3-8. doi: 10.1002/path.4933. Epub 2017 Aug 7. J Pathol. 2017. PMID: 28682481
KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype.
Clipson A, Wang M, de Leval L, Ashton-Key M, Wotherspoon A, Vassiliou G, Bolli N, Grove C, Moody S, Escudero-Ibarz L, Gundem G, Brugger K, Xue X, Mi E, Bench A, Scott M, Liu H, Follows G, Robles EF, Martinez-Climent JA, Oscier D, Watkins AJ, Du MQ. Clipson A, et al. Among authors: escudero ibarz l. Leukemia. 2015 May;29(5):1177-85. doi: 10.1038/leu.2014.330. Epub 2014 Nov 27. Leukemia. 2015. PMID: 25428260
Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice.
O' Donovan DH, Baker D, Ciotta G, Degorce SL, Demanze S, Dockerill M, Escudero-Ibarz L, Ireland L, Mao Y, Packer MJ, Robinson J, Scarfe G, Tang H, Valge-Archer V. O' Donovan DH, et al. Among authors: escudero ibarz l. Bioorg Med Chem Lett. 2023 Nov 15;96:129518. doi: 10.1016/j.bmcl.2023.129518. Epub 2023 Oct 12. Bioorg Med Chem Lett. 2023. PMID: 37838344
Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF.
Monkley S, Overed-Sayer C, Parfrey H, Rassl D, Crowther D, Escudero-Ibarz L, Davis N, Carruthers A, Berks R, Coetzee M, Kolosionek E, Karlsson M, Griffin LR, Clausen M, Belfield G, Hogaboam CM, Murray LA. Monkley S, et al. Among authors: escudero ibarz l. Sci Rep. 2021 Nov 3;11(1):21584. doi: 10.1038/s41598-021-00769-7. Sci Rep. 2021. PMID: 34732748 Free PMC article.