Sharma RB - Search Results

1

Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.

Stamateris RE, Sharma RB, Kong Y, Ebrahimpour P, Panday D, Ranganath P, Zou B, Levitt H, Parambil NA, O'Donnell CP, García-Ocaña A, Alonso LC. Stamateris RE, et al. Among authors: sharma rb. Diabetes. 2016 Apr;65(4):981-95. doi: 10.2337/db15-0529. Epub 2016 Jan 6. Diabetes. 2016. PMID: 26740601 Free PMC article.

2

Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression.

Stamateris RE, Sharma RB, Hollern DA, Alonso LC. Stamateris RE, et al. Among authors: sharma rb. Am J Physiol Endocrinol Metab. 2013 Jul 1;305(1):E149-59. doi: 10.1152/ajpendo.00040.2013. Epub 2013 May 14. Am J Physiol Endocrinol Metab. 2013. PMID: 23673159 Free PMC article.

3

Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well?

Sharma RB, Alonso LC. Sharma RB, et al. Curr Diab Rep. 2014 Jun;14(6):492. doi: 10.1007/s11892-014-0492-2. Curr Diab Rep. 2014. PMID: 24740729 Free PMC article. Review.

4

Insulin demand regulates β cell number via the unfolded protein response.

Sharma RB, O'Donnell AC, Stamateris RE, Ha B, McCloskey KM, Reynolds PR, Arvan P, Alonso LC. Sharma RB, et al. J Clin Invest. 2015 Oct 1;125(10):3831-46. doi: 10.1172/JCI79264. Epub 2015 Sep 21. J Clin Invest. 2015. PMID: 26389675 Free PMC article.

5

Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice.

Singamsetty S, Shah FA, Guo L, Watanabe Y, McDonald S, Sharma R, Zhang Y, Alonso LC, O'Donnell CP, McVerry BJ. Singamsetty S, et al. Appl Physiol Nutr Metab. 2016 Jan;41(1):12-9. doi: 10.1139/apnm-2015-0213. Epub 2015 Sep 9. Appl Physiol Nutr Metab. 2016. PMID: 26624964 Free PMC article.

6

In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.

Choudhury SR, Fitzpatrick Z, Harris AF, Maitland SA, Ferreira JS, Zhang Y, Ma S, Sharma RB, Gray-Edwards HL, Johnson JA, Johnson AK, Alonso LC, Punzo C, Wagner KR, Maguire CA, Kotin RM, Martin DR, Sena-Esteves M. Choudhury SR, et al. Among authors: sharma rb. Mol Ther. 2016 Aug;24(7):1247-57. doi: 10.1038/mt.2016.84. Epub 2016 Apr 27. Mol Ther. 2016. PMID: 27117222 Free PMC article.

7

Islet biology, the CDKN2A/B locus and type 2 diabetes risk.

Kong Y, Sharma RB, Nwosu BU, Alonso LC. Kong Y, et al. Among authors: sharma rb. Diabetologia. 2016 Aug;59(8):1579-93. doi: 10.1007/s00125-016-3967-7. Epub 2016 May 7. Diabetologia. 2016. PMID: 27155872 Free PMC article. Review.

8

Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.

Roth Flach RJ, Danai LV, DiStefano MT, Kelly M, Menendez LG, Jurczyk A, Sharma RB, Jung DY, Kim JH, Kim JK, Bortell R, Alonso LC, Czech MP. Roth Flach RJ, et al. Among authors: sharma rb. J Biol Chem. 2016 Jul 29;291(31):16221-30. doi: 10.1074/jbc.M116.718932. Epub 2016 May 20. J Biol Chem. 2016. PMID: 27226575 Free PMC article.

9

CDKN2A/B T2D Genome-Wide Association Study Risk SNPs Impact Locus Gene Expression and Proliferation in Human Islets.

Kong Y, Sharma RB, Ly S, Stamateris RE, Jesdale WM, Alonso LC. Kong Y, et al. Among authors: sharma rb. Diabetes. 2018 May;67(5):872-884. doi: 10.2337/db17-1055. Epub 2018 Feb 6. Diabetes. 2018. PMID: 29432124 Free PMC article.

10

DNA Damage Does Not Cause BrdU Labeling of Mouse or Human β-Cells.

Sharma RB, Darko C, Zheng X, Gablaski B, Alonso LC. Sharma RB, et al. Diabetes. 2019 May;68(5):975-987. doi: 10.2337/db18-0761. Epub 2019 Mar 4. Diabetes. 2019. PMID: 30833468 Free PMC article.

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