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ESTRO-ACROP guideline "target delineation of glioblastomas".
Niyazi M, Brada M, Chalmers AJ, Combs SE, Erridge SC, Fiorentino A, Grosu AL, Lagerwaard FJ, Minniti G, Mirimanoff RO, Ricardi U, Short SC, Weber DC, Belka C. Niyazi M, et al. Among authors: chalmers aj. Radiother Oncol. 2016 Jan;118(1):35-42. doi: 10.1016/j.radonc.2015.12.003. Epub 2016 Jan 6. Radiother Oncol. 2016. PMID: 26777122
PARADIGM-2: Two parallel phase I studies of olaparib and radiotherapy or olaparib and radiotherapy plus temozolomide in patients with newly diagnosed glioblastoma, with treatment stratified by MGMT status.
Fulton B, Short SC, James A, Nowicki S, McBain C, Jefferies S, Kelly C, Stobo J, Morris A, Williamson A, Chalmers AJ. Fulton B, et al. Among authors: chalmers aj. Clin Transl Radiat Oncol. 2017 Nov 21;8:12-16. doi: 10.1016/j.ctro.2017.11.003. eCollection 2018 Jan. Clin Transl Radiat Oncol. 2017. PMID: 29594237 Free PMC article.
Pharmacokinetics, safety, and tolerability of olaparib and temozolomide for recurrent glioblastoma: results of the phase I OPARATIC trial.
Hanna C, Kurian KM, Williams K, Watts C, Jackson A, Carruthers R, Strathdee K, Cruickshank G, Dunn L, Erridge S, Godfrey L, Jefferies S, McBain C, Sleigh R, McCormick A, Pittman M, Halford S, Chalmers AJ. Hanna C, et al. Among authors: chalmers aj. Neuro Oncol. 2020 Dec 18;22(12):1840-1850. doi: 10.1093/neuonc/noaa104. Neuro Oncol. 2020. PMID: 32347934 Free PMC article. Clinical Trial.
Hydroxychloroquine and short-course radiotherapy in elderly patients with newly diagnosed high-grade glioma: a randomized phase II trial.
Brazil L, Swampillai AL, Mak KM, Edwards D, Mesiri P, Clifton-Hadley L, Shaffer R, Lewis J, Watts C, Jeffries S, Gkogkou P, Chalmers AJ, Fersht NL, Hackshaw A, Short SC. Brazil L, et al. Among authors: chalmers aj. Neurooncol Adv. 2020 Apr 27;2(1):vdaa046. doi: 10.1093/noajnl/vdaa046. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32642699 Free PMC article.
Correcting the drug development paradigm for glioblastoma requires serial tissue sampling.
Singh K, Hotchkiss KM, Parney IF, De Groot J, Sahebjam S, Sanai N, Platten M, Galanis E, Lim M, Wen PY, Minniti G, Colman H, Cloughesy TF, Mehta MP, Geurts M, Arrillaga-Romany I, Desjardins A, Tanner K, Short S, Arons D, Duke E, Wick W, Bagley SJ, Ashley DM, Kumthekar P, Verhaak R, Chalmers AJ, Patel AP, Watts C, Fecci PE, Batchelor TT, Weller M, Vogelbaum MA, Preusser M, Berger MS, Khasraw M. Singh K, et al. Among authors: chalmers aj. Nat Med. 2023 Oct;29(10):2402-2405. doi: 10.1038/s41591-023-02464-8. Nat Med. 2023. PMID: 37488293 No abstract available.
Concurrent Olaparib and Radiation Therapy in Older Patients With Newly Diagnosed Glioblastoma: The Phase 1 Dose-Escalation PARADIGM Trial.
Derby S, Jackson MR, Williams K, Stobo J, Kelly C, Sweeting L, Shad S, Herbert C, Short SC, Williamson A, James A, Nowicki S, Bulbeck H, Chalmers AJ. Derby S, et al. Among authors: chalmers aj. Int J Radiat Oncol Biol Phys. 2024 Apr 1;118(5):1371-1378. doi: 10.1016/j.ijrobp.2024.01.011. Epub 2024 Jan 9. Int J Radiat Oncol Biol Phys. 2024. PMID: 38211641 Free article. Clinical Trial.
122 results