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Page 1
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, Lamming DW, Dogum R, Guo G, Bell GW, Selig M, Nielsen GP, Gupta N, Ferrone CR, Deshpande V, Yuan GC, Orkin SH, Sabatini DM, Yilmaz ÖH. Beyaz S, et al. Among authors: roper j. Nature. 2016 Mar 3;531(7592):53-8. doi: 10.1038/nature17173. Nature. 2016. PMID: 26935695 Free PMC article.
Colorectal cancer models for novel drug discovery.
Golovko D, Kedrin D, Yilmaz ÖH, Roper J. Golovko D, et al. Among authors: roper j. Expert Opin Drug Discov. 2015;10(11):1217-29. doi: 10.1517/17460441.2015.1079618. Epub 2015 Aug 21. Expert Opin Drug Discov. 2015. PMID: 26295972 Free PMC article. Review.
In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera FJ, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Roper J, et al. Nat Biotechnol. 2017 Jun;35(6):569-576. doi: 10.1038/nbt.3836. Epub 2017 May 1. Nat Biotechnol. 2017. PMID: 28459449 Free PMC article.
Metabolic Teamwork in the Stem Cell Niche.
Roper J, Yilmaz ÖH. Roper J, et al. Cell Metab. 2017 May 2;25(5):993-994. doi: 10.1016/j.cmet.2017.04.019. Cell Metab. 2017. PMID: 28467944 Free PMC article.
PKM2 is not required for colon cancer initiated by APC loss.
Lau AN, Israelsen WJ, Roper J, Sinnamon MJ, Georgeon L, Dayton TL, Hillis AL, Yilmaz OH, Di Vizio D, Hung KE, Vander Heiden MG. Lau AN, et al. Among authors: roper j. Cancer Metab. 2017 Nov 30;5:10. doi: 10.1186/s40170-017-0172-1. eCollection 2017. Cancer Metab. 2017. PMID: 29214019 Free PMC article.
Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Roper J, et al. Nat Biotechnol. 2017 Dec 8;35(12):1211. doi: 10.1038/nbt1217-1211a. Nat Biotechnol. 2017. PMID: 29220013
Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, Kobayashi H, Putoczki TL, Hayakawa Y, Leedham SJ, Abud HE, Yilmaz ÖH, Marker J, Klebe S, Wirapati P, Mukherjee S, Tejpar S, Leggett BA, Whitehall VLJ, Worthley DL, Woods SL. Lannagan TRM, et al. Among authors: roper j. Gut. 2019 Apr;68(4):684-692. doi: 10.1136/gutjnl-2017-315920. Epub 2018 Apr 17. Gut. 2019. PMID: 29666172 Free PMC article.
457 results