Flynn HR - Search Results

1

Phosphorylation acts positively and negatively to regulate MRTF-A subcellular localisation and activity.

Panayiotou R, Miralles F, Pawlowski R, Diring J, Flynn HR, Skehel M, Treisman R. Panayiotou R, et al. Among authors: flynn hr. Elife. 2016 Jun 15;5:e15460. doi: 10.7554/eLife.15460. Elife. 2016. PMID: 27304076 Free PMC article.

2

Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion.

Rolef Ben-Shahar T, Heeger S, Lehane C, East P, Flynn H, Skehel M, Uhlmann F. Rolef Ben-Shahar T, et al. Science. 2008 Jul 25;321(5888):563-6. doi: 10.1126/science.1157774. Science. 2008. PMID: 18653893

3

Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.

Fedoryshchak RO, Přechová M, Butler AM, Lee R, O'Reilly N, Flynn HR, Snijders AP, Eder N, Ultanir S, Mouilleron S, Treisman R. Fedoryshchak RO, et al. Among authors: flynn hr. Elife. 2020 Sep 25;9:e61509. doi: 10.7554/eLife.61509. Elife. 2020. PMID: 32975518 Free PMC article.

4

Cell-specific bioorthogonal tagging of glycoproteins.

Cioce A, Calle B, Rizou T, Lowery SC, Bridgeman VL, Mahoney KE, Marchesi A, Bineva-Todd G, Flynn H, Li Z, Tastan OY, Roustan C, Soro-Barrio P, Rafiee MR, Garza-Garcia A, Antonopoulos A, Wood TM, Keenan T, Both P, Huang K, Parmeggian F, Snijders AP, Skehel M, Kjær S, Fascione MA, Bertozzi CR, Haslam SM, Flitsch SL, Malaker SA, Malanchi I, Schumann B. Cioce A, et al. Nat Commun. 2022 Oct 25;13(1):6237. doi: 10.1038/s41467-022-33854-0. Nat Commun. 2022. PMID: 36284108 Free PMC article.

5

Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration.

Roşianu F, Mihaylov SR, Eder N, Martiniuc A, Claxton S, Flynn HR, Jalal S, Domart MC, Collinson L, Skehel M, Snijders AP, Krause M, Tooze SA, Ultanir SK. Roşianu F, et al. Among authors: flynn hr. Life Sci Alliance. 2022 Nov 29;6(2):e202201712. doi: 10.26508/lsa.202201712. Print 2023 Feb. Life Sci Alliance. 2022. PMID: 36446521 Free PMC article.

6

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.

Ahel D, Horejsí Z, Wiechens N, Polo SE, Garcia-Wilson E, Ahel I, Flynn H, Skehel M, West SC, Jackson SP, Owen-Hughes T, Boulton SJ. Ahel D, et al. Science. 2009 Sep 4;325(5945):1240-3. doi: 10.1126/science.1177321. Epub 2009 Aug 6. Science. 2009. PMID: 19661379 Free PMC article.

7

Hos1 deacetylates Smc3 to close the cohesin acetylation cycle.

Borges V, Lehane C, Lopez-Serra L, Flynn H, Skehel M, Rolef Ben-Shahar T, Uhlmann F. Borges V, et al. Mol Cell. 2010 Sep 10;39(5):677-88. doi: 10.1016/j.molcel.2010.08.009. Mol Cell. 2010. PMID: 20832720 Free article.

8

Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1.

Smith E, Hégarat N, Vesely C, Roseboom I, Larch C, Streicher H, Straatman K, Flynn H, Skehel M, Hirota T, Kuriyama R, Hochegger H. Smith E, et al. EMBO J. 2011 Jun 1;30(11):2233-45. doi: 10.1038/emboj.2011.120. Epub 2011 Apr 26. EMBO J. 2011. PMID: 21522128 Free PMC article.

9

Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex.

Hořejší Z, Stach L, Flower TG, Joshi D, Flynn H, Skehel JM, O'Reilly NJ, Ogrodowicz RW, Smerdon SJ, Boulton SJ. Hořejší Z, et al. Cell Rep. 2014 Apr 10;7(1):19-26. doi: 10.1016/j.celrep.2014.03.013. Epub 2014 Mar 20. Cell Rep. 2014. PMID: 24656813 Free PMC article.

10

CDK Substrate Phosphorylation and Ordering the Cell Cycle.

Swaffer MP, Jones AW, Flynn HR, Snijders AP, Nurse P. Swaffer MP, et al. Among authors: flynn hr. Cell. 2016 Dec 15;167(7):1750-1761.e16. doi: 10.1016/j.cell.2016.11.034. Cell. 2016. PMID: 27984725 Free PMC article.

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