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Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy.
Paholak HJ, Stevers NO, Chen H, Burnett JP, He M, Korkaya H, McDermott SP, Deol Y, Clouthier SG, Luther T, Li Q, Wicha MS, Sun D. Paholak HJ, et al. Among authors: clouthier sg. Biomaterials. 2016 Oct;104:145-57. doi: 10.1016/j.biomaterials.2016.06.045. Epub 2016 Jun 23. Biomaterials. 2016. PMID: 27450902 Free PMC article.
Role of microRNAs in the regulation of breast cancer stem cells.
Liu S, Clouthier SG, Wicha MS. Liu S, et al. Among authors: clouthier sg. J Mammary Gland Biol Neoplasia. 2012 Mar;17(1):15-21. doi: 10.1007/s10911-012-9242-8. Epub 2012 Feb 14. J Mammary Gland Biol Neoplasia. 2012. PMID: 22331423 Free PMC article.
Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population.
Korkaya H, Kim GI, Davis A, Malik F, Henry NL, Ithimakin S, Quraishi AA, Tawakkol N, D'Angelo R, Paulson AK, Chung S, Luther T, Paholak HJ, Liu S, Hassan KA, Zen Q, Clouthier SG, Wicha MS. Korkaya H, et al. Among authors: clouthier sg. Mol Cell. 2012 Aug 24;47(4):570-84. doi: 10.1016/j.molcel.2012.06.014. Epub 2012 Jul 19. Mol Cell. 2012. PMID: 22819326 Free PMC article.
Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts.
Liu S, Cong Y, Wang D, Sun Y, Deng L, Liu Y, Martin-Trevino R, Shang L, McDermott SP, Landis MD, Hong S, Adams A, D'Angelo R, Ginestier C, Charafe-Jauffret E, Clouthier SG, Birnbaum D, Wong ST, Zhan M, Chang JC, Wicha MS. Liu S, et al. Among authors: clouthier sg. Stem Cell Reports. 2013 Dec 27;2(1):78-91. doi: 10.1016/j.stemcr.2013.11.009. eCollection 2014 Jan 14. Stem Cell Reports. 2013. PMID: 24511467 Free PMC article.
CRLX101, an investigational camptothecin-containing nanoparticle-drug conjugate, targets cancer stem cells and impedes resistance to antiangiogenic therapy in mouse models of breast cancer.
Conley SJ, Baker TL, Burnett JP, Theisen RL, Lazarus D, Peters CG, Clouthier SG, Eliasof S, Wicha MS. Conley SJ, et al. Among authors: clouthier sg. Breast Cancer Res Treat. 2015 Apr;150(3):559-67. doi: 10.1007/s10549-015-3349-8. Epub 2015 Apr 2. Breast Cancer Res Treat. 2015. PMID: 25833208
Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling.
Korkaya H, Paulson A, Charafe-Jauffret E, Ginestier C, Brown M, Dutcher J, Clouthier SG, Wicha MS. Korkaya H, et al. Among authors: clouthier sg. PLoS Biol. 2009 Jun 2;7(6):e1000121. doi: 10.1371/journal.pbio.1000121. Epub 2009 Jun 2. PLoS Biol. 2009. PMID: 19492080 Free PMC article.
44 results