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Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.
Leithner A, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, de Gorter DJ, Schur F, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai FP, Moser M, Kerjaschki D, Rottner K, Small JV, Stradal TE, Sixt M. Leithner A, et al. Among authors: schur f. Nat Cell Biol. 2016 Nov;18(11):1253-1259. doi: 10.1038/ncb3426. Epub 2016 Oct 24. Nat Cell Biol. 2016. PMID: 27775702
Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin.
Koestler SA, Steffen A, Nemethova M, Winterhoff M, Luo N, Holleboom JM, Krupp J, Jacob S, Vinzenz M, Schur F, Schlüter K, Gunning PW, Winkler C, Schmeiser C, Faix J, Stradal TE, Small JV, Rottner K. Koestler SA, et al. Among authors: schur f. Mol Biol Cell. 2013 Sep;24(18):2861-75. doi: 10.1091/mbc.E12-12-0857. Epub 2013 Jul 24. Mol Biol Cell. 2013. PMID: 23885122 Free PMC article.
Actin branching in the initiation and maintenance of lamellipodia.
Vinzenz M, Nemethova M, Schur F, Mueller J, Narita A, Urban E, Winkler C, Schmeiser C, Koestler SA, Rottner K, Resch GP, Maeda Y, Small JV. Vinzenz M, et al. Among authors: schur f. J Cell Sci. 2012 Jun 1;125(Pt 11):2775-85. doi: 10.1242/jcs.107623. Epub 2012 Mar 19. J Cell Sci. 2012. PMID: 22431015
Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation.
Steffen A, Ladwein M, Dimchev GA, Hein A, Schwenkmezger L, Arens S, Ladwein KI, Margit Holleboom J, Schur F, Victor Small J, Schwarz J, Gerhard R, Faix J, Stradal TE, Brakebusch C, Rottner K. Steffen A, et al. Among authors: schur f. J Cell Sci. 2013 Oct 15;126(Pt 20):4572-88. doi: 10.1242/jcs.118232. Epub 2013 Jul 31. J Cell Sci. 2013. PMID: 23902686 Free PMC article.
Inositol phosphates are assembly co-factors for HIV-1.
Dick RA, Zadrozny KK, Xu C, Schur FKM, Lyddon TD, Ricana CL, Wagner JM, Perilla JR, Ganser-Pornillos BK, Johnson MC, Pornillos O, Vogt VM. Dick RA, et al. Nature. 2018 Aug;560(7719):509-512. doi: 10.1038/s41586-018-0396-4. Epub 2018 Aug 1. Nature. 2018. PMID: 30069050 Free PMC article.
34 results