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Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.
Leithner A, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, de Gorter DJ, Schur F, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai FP, Moser M, Kerjaschki D, Rottner K, Small JV, Stradal TE, Sixt M. Leithner A, et al. Among authors: de gorter dj. Nat Cell Biol. 2016 Nov;18(11):1253-1259. doi: 10.1038/ncb3426. Epub 2016 Oct 24. Nat Cell Biol. 2016. PMID: 27775702
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion.
Stahnke S, Döring H, Kusch C, de Gorter DJJ, Dütting S, Guledani A, Pleines I, Schnoor M, Sixt M, Geffers R, Rohde M, Müsken M, Kage F, Steffen A, Faix J, Nieswandt B, Rottner K, Stradal TEB. Stahnke S, et al. Among authors: de gorter djj. Curr Biol. 2021 May 24;31(10):2051-2064.e8. doi: 10.1016/j.cub.2021.02.043. Epub 2021 Mar 11. Curr Biol. 2021. PMID: 33711252 Free article.
Inhibition of the transforming growth factor beta (TGFbeta) pathway by interleukin-1beta is mediated through TGFbeta-activated kinase 1 phosphorylation of SMAD3.
Benus GF, Wierenga AT, de Gorter DJ, Schuringa JJ, van Bennekum AM, Drenth-Diephuis L, Vellenga E, Eggen BJ. Benus GF, et al. Among authors: de gorter dj. Mol Biol Cell. 2005 Aug;16(8):3501-10. doi: 10.1091/mbc.e04-11-1033. Epub 2005 May 25. Mol Biol Cell. 2005. PMID: 15917296 Free PMC article.
Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis.
Beckmann D, Römer-Hillmann A, Krause A, Hansen U, Wehmeyer C, Intemann J, de Gorter DJJ, Dankbar B, Hillen J, Heitzmann M, Begemann I, Galic M, Weinhage T, Foell D, Ai R, Kremerskothen J, Kiener HP, Müller S, Kamradt T, Schröder C, Leitão E, Horsthemke B, Rosenstiel P, Nordström K, Gasparoni G, Gasparoni N, Walter J, Li N, Yang X, Chung HR, Pavenstädt H, Lindemann N, Schnittler HJ, Wang W, Firestein GS, Pap T, Korb-Pap A. Beckmann D, et al. Among authors: de gorter djj. Nat Commun. 2021 Jun 15;12(1):3624. doi: 10.1038/s41467-021-23706-8. Nat Commun. 2021. PMID: 34131132 Free PMC article.
ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation.
van Dinther M, Visser N, de Gorter DJ, Doorn J, Goumans MJ, de Boer J, ten Dijke P. van Dinther M, et al. Among authors: de boer j, de gorter dj. J Bone Miner Res. 2010 Jun;25(6):1208-15. doi: 10.1359/jbmr.091110. J Bone Miner Res. 2010. PMID: 19929436 Free article.
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