Iaconelli J - Search Results

1

Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells.

Iaconelli J, Lalonde J, Watmuff B, Liu B, Mazitschek R, Haggarty SJ, Karmacharya R. Iaconelli J, et al. ACS Chem Biol. 2017 Aug 18;12(8):2139-2148. doi: 10.1021/acschembio.6b01014. Epub 2017 Jul 10. ACS Chem Biol. 2017. PMID: 28628306 Free PMC article.

2

HDAC6 inhibitors modulate Lys49 acetylation and membrane localization of β-catenin in human iPSC-derived neuronal cells.

Iaconelli J, Huang JH, Berkovitch SS, Chattopadhyay S, Mazitschek R, Schreiber SL, Haggarty SJ, Karmacharya R. Iaconelli J, et al. ACS Chem Biol. 2015 Mar 20;10(3):883-90. doi: 10.1021/cb500838r. Epub 2015 Jan 8. ACS Chem Biol. 2015. PMID: 25546293 Free PMC article.

3

HDAC6 Modulates Signaling Pathways Relevant to Synaptic Biology and Neuronal Differentiation in Human Stem-Cell-Derived Neurons.

Iaconelli J, Xuan L, Karmacharya R. Iaconelli J, et al. Int J Mol Sci. 2019 Mar 31;20(7):1605. doi: 10.3390/ijms20071605. Int J Mol Sci. 2019. PMID: 30935091 Free PMC article. Review.

4

Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells.

Watmuff B, Berkovitch SS, Huang JH, Iaconelli J, Toffel S, Karmacharya R. Watmuff B, et al. Among authors: iaconelli j. Mol Cell Neurosci. 2016 Jun;73:96-103. doi: 10.1016/j.mcn.2016.01.003. Epub 2016 Jan 14. Mol Cell Neurosci. 2016. PMID: 26777134 Free PMC article. Review.

5

Perturbational Profiling of Metabolites in Patient Fibroblasts Implicates α-Aminoadipate as a Potential Biomarker for Bipolar Disorder.

Huang JH, Berkovitch SS, Iaconelli J, Watmuff B, Park H, Chattopadhyay S, McPhie D, Öngür D, Cohen BM, Clish CB, Karmacharya R. Huang JH, et al. Among authors: iaconelli j. Mol Neuropsychiatry. 2016 Jul;2(2):97-106. doi: 10.1159/000446654. Epub 2016 Jun 24. Mol Neuropsychiatry. 2016. PMID: 27606323 Free PMC article.

6

Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines.

Huang JH, Park H, Iaconelli J, Berkovitch SS, Watmuff B, McPhie D, Öngür D, Cohen BM, Clish CB, Karmacharya R. Huang JH, et al. Among authors: iaconelli j. J Proteome Res. 2017 Feb 3;16(2):481-493. doi: 10.1021/acs.jproteome.6b00628. Epub 2016 Nov 28. J Proteome Res. 2017. PMID: 28152600

7

Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.

Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Subramanian R, Carmody LC, Yusuf RZ, Sykes DB, Paulk J, Vetere A, Vallet S, Santo L, Cirstea DD, Hideshima T, Dančík V, Majireck MM, Hussain MM, Singh S, Quiroz R, Iaconelli J, Karmacharya R, Tolliday NJ, Clemons PA, Moore MAS, Stern AM, Shamji AF, Ebert BL, Golub TR, Raje NS, Scadden DT, Schreiber SL. Chattopadhyay S, et al. Among authors: iaconelli j. Cell Rep. 2015 Feb 10;10(5):755-770. doi: 10.1016/j.celrep.2015.01.017. Epub 2015 Feb 5. Cell Rep. 2015. PMID: 25660025 Free PMC article.

8

YAP-dependent proliferation by a small molecule targeting annexin A2.

Shalhout SZ, Yang PY, Grzelak EM, Nutsch K, Shao S, Zambaldo C, Iaconelli J, Ibrahim L, Stanton C, Chadwick SR, Chen E, DeRan M, Li S, Hull M, Wu X, Chatterjee AK, Shen W, Camargo FD, Schultz PG, Bollong MJ. Shalhout SZ, et al. Among authors: iaconelli j. Nat Chem Biol. 2021 Jul;17(7):767-775. doi: 10.1038/s41589-021-00755-0. Epub 2021 Mar 15. Nat Chem Biol. 2021. PMID: 33723431

9

Small-Molecule Stimulators of NRF1 Transcriptional Activity.

Iaconelli J, Ibrahim L, Chen E, Hull M, Schultz PG, Bollong MJ. Iaconelli J, et al. Chembiochem. 2020 Jul 1;21(13):1816-1819. doi: 10.1002/cbic.201900487. Epub 2019 Nov 8. Chembiochem. 2020. PMID: 31596542

10

Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activators.

Jo J, Ibrahim L, Iaconelli J, Kwak J, Kumar M, Jung Y, Lairson LL, Chatterjee AK, Schultz PG, Bollong MJ, Yun H. Jo J, et al. Among authors: iaconelli j. Bioorg Chem. 2021 Mar;108:104614. doi: 10.1016/j.bioorg.2020.104614. Epub 2021 Jan 5. Bioorg Chem. 2021. PMID: 33508678

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