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Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils.
Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ. Engblom C, et al. Among authors: severe n. Science. 2017 Dec 1;358(6367):eaal5081. doi: 10.1126/science.aal5081. Science. 2017. PMID: 29191879 Free PMC article.
Ischemic stroke activates hematopoietic bone marrow stem cells.
Courties G, Herisson F, Sager HB, Heidt T, Ye Y, Wei Y, Sun Y, Severe N, Dutta P, Scharff J, Scadden DT, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M. Courties G, et al. Among authors: severe n. Circ Res. 2015 Jan 30;116(3):407-17. doi: 10.1161/CIRCRESAHA.116.305207. Epub 2014 Oct 31. Circ Res. 2015. PMID: 25362208 Free PMC article.
Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke.
Courties G, Frodermann V, Honold L, Zheng Y, Herisson F, Schloss MJ, Sun Y, Presumey J, Severe N, Engblom C, Hulsmans M, Cremer S, Rohde D, Pittet MJ, Scadden DT, Swirski FK, Kim DE, Moskowitz MA, Nahrendorf M. Courties G, et al. Among authors: severe n. Circ Res. 2019 Apr 26;124(9):1372-1385. doi: 10.1161/CIRCRESAHA.118.314518. Circ Res. 2019. PMID: 30782088 Free PMC article.
A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia.
Baryawno N, Przybylski D, Kowalczyk MS, Kfoury Y, Severe N, Gustafsson K, Kokkaliaris KD, Mercier F, Tabaka M, Hofree M, Dionne D, Papazian A, Lee D, Ashenberg O, Subramanian A, Vaishnav ED, Rozenblatt-Rosen O, Regev A, Scadden DT. Baryawno N, et al. Among authors: severe n. Cell. 2019 Jun 13;177(7):1915-1932.e16. doi: 10.1016/j.cell.2019.04.040. Epub 2019 May 23. Cell. 2019. PMID: 31130381 Free PMC article.
Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping.
Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT. Severe N, et al. Cell Stem Cell. 2019 Oct 3;25(4):570-583.e7. doi: 10.1016/j.stem.2019.06.003. Epub 2019 Jul 3. Cell Stem Cell. 2019. PMID: 31279774 Free PMC article.
B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.
Schloss MJ, Hulsmans M, Rohde D, Lee IH, Severe N, Foy BH, Pulous FE, Zhang S, Kokkaliaris KD, Frodermann V, Courties G, Yang C, Iwamoto Y, Knudsen AS, McAlpine CS, Yamazoe M, Schmidt SP, Wojtkiewicz GR, Masson GS, Gustafsson K, Capen D, Brown D, Higgins JM, Scadden DT, Libby P, Swirski FK, Naxerova K, Nahrendorf M. Schloss MJ, et al. Among authors: severe n. Nat Immunol. 2022 Apr;23(4):605-618. doi: 10.1038/s41590-022-01165-7. Epub 2022 Mar 28. Nat Immunol. 2022. PMID: 35352063 Free PMC article.
Bone marrow drives central nervous system regeneration after radiation injury.
Dietrich J, Baryawno N, Nayyar N, Valtis YK, Yang B, Ly I, Besnard A, Severe N, Gustafsson KU, Andronesi OC, Batchelor TT, Sahay A, Scadden DT. Dietrich J, et al. Among authors: severe n. J Clin Invest. 2018 Jan 2;128(1):281-293. doi: 10.1172/JCI90647. Epub 2017 Dec 4. J Clin Invest. 2018. PMID: 29202481 Free PMC article.
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