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c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.
Edmunds LR, Sharma L, Kang A, Lu J, Vockley J, Basu S, Uppala R, Goetzman ES, Beck ME, Scott D, Prochownik EV. Edmunds LR, et al. Among authors: prochownik ev. J Biol Chem. 2014 Sep 5;289(36):25382-92. doi: 10.1074/jbc.M114.580662. Epub 2014 Jul 22. J Biol Chem. 2014. PMID: 25053415 Free PMC article.
Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes.
Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV. Edmunds LR, et al. Among authors: prochownik ev. Oncotarget. 2016 May 24;7(21):30379-95. doi: 10.18632/oncotarget.8856. Oncotarget. 2016. PMID: 27105497 Free PMC article.
Inhibition of hepatocellular carcinoma by metabolic normalization.
Wang H, Lu J, Dolezal J, Kulkarni S, Zhang W, Chen A, Gorka J, Mandel JA, Prochownik EV. Wang H, et al. Among authors: prochownik ev. PLoS One. 2019 Jun 26;14(6):e0218186. doi: 10.1371/journal.pone.0218186. eCollection 2019. PLoS One. 2019. PMID: 31242205 Free PMC article.
Genetic dissection of c-myc apoptotic pathways.
Nesbit CE, Tersak JM, Grove LE, Drzal A, Choi H, Prochownik EV. Nesbit CE, et al. Among authors: prochownik ev. Oncogene. 2000 Jun 29;19(28):3200-12. doi: 10.1038/sj.onc.1203636. Oncogene. 2000. PMID: 10918575
172 results