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Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.
Guo CJ, Chang FY, Wyche TP, Backus KM, Acker TM, Funabashi M, Taketani M, Donia MS, Nayfach S, Pollard KS, Craik CS, Cravatt BF, Clardy J, Voigt CA, Fischbach MA. Guo CJ, et al. Cell. 2017 Jan 26;168(3):517-526.e18. doi: 10.1016/j.cell.2016.12.021. Epub 2017 Jan 19. Cell. 2017. PMID: 28111075 Free PMC article.
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential.
Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, Tang WHW, Lusis AJ, Rey FE, Fischbach MA, Hazen SL. Skye SM, et al. Among authors: guo cj. Circ Res. 2018 Oct 26;123(10):1164-1176. doi: 10.1161/CIRCRESAHA.118.313142. Circ Res. 2018. PMID: 30359185 Free PMC article. Clinical Trial.
A metabolic pathway for bile acid dehydroxylation by the gut microbiome.
Funabashi M, Grove TL, Wang M, Varma Y, McFadden ME, Brown LC, Guo C, Higginbottom S, Almo SC, Fischbach MA. Funabashi M, et al. Nature. 2020 Jun;582(7813):566-570. doi: 10.1038/s41586-020-2396-4. Epub 2020 Jun 17. Nature. 2020. PMID: 32555455 Free PMC article.
Modulating microbiome metabolites in vivo.
Guo CJ. Guo CJ. Science. 2020 Jul 10;369(6500):153. doi: 10.1126/science.abc5620. Science. 2020. PMID: 32646995 No abstract available.
Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation.
Arifuzzaman M, Won TH, Li TT, Yano H, Digumarthi S, Heras AF, Zhang W, Parkhurst CN, Kashyap S, Jin WB, Putzel GG, Tsou AM, Chu C, Wei Q, Grier A; JRI IBD Live Cell Bank Consortium; Worgall S, Guo CJ, Schroeder FC, Artis D. Arifuzzaman M, et al. Among authors: guo cj. Nature. 2022 Nov;611(7936):578-584. doi: 10.1038/s41586-022-05380-y. Epub 2022 Nov 2. Nature. 2022. PMID: 36323778 Free PMC article.
Gut bacteria-derived serotonin promotes immune tolerance in early life.
Sanidad KZ, Rager SL, Carrow HC, Ananthanarayanan A, Callaghan R, Hart LR, Li T, Ravisankar P, Brown JA, Amir M, Jin JC, Savage AR, Luo R, Rowdo FM, Martin ML, Silver RB, Guo CJ, Krumsiek J, Inohara N, Zeng MY. Sanidad KZ, et al. Among authors: guo cj. Sci Immunol. 2024 Mar 15;9(93):eadj4775. doi: 10.1126/sciimmunol.adj4775. Epub 2024 Mar 15. Sci Immunol. 2024. PMID: 38489352
235 results