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Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype.
Hanna SJ, Powell WE, Long AE, Robinson EJS, Davies J, Megson C, Howell A, Jones TJ, Ladell K, Price DA, Dayan CM, Williams AJK, Gillespie KM, Wong FS. Hanna SJ, et al. Among authors: long ae. Diabetologia. 2020 Jun;63(6):1174-1185. doi: 10.1007/s00125-020-05114-7. Epub 2020 Mar 10. Diabetologia. 2020. PMID: 32157332 Free PMC article.
A quarter of patients with type 1 diabetes have co-existing non-islet autoimmunity: the findings of a UK population-based family study.
Kozhakhmetova A, Wyatt RC, Caygill C, Williams C, Long AE, Chandler K, Aitken RJ, Wenzlau JM, Davidson HW, Gillespie KM, Williams AJK. Kozhakhmetova A, et al. Among authors: long ae. Clin Exp Immunol. 2018 Jun;192(3):251-258. doi: 10.1111/cei.13115. Epub 2018 Mar 24. Clin Exp Immunol. 2018. PMID: 29431870 Free PMC article.
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