Melton DA - Search Results

1

A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion.

Helman A, Cangelosi AL, Davis JC, Pham Q, Rothman A, Faust AL, Straubhaar JR, Sabatini DM, Melton DA. Helman A, et al. Among authors: melton da. Cell Metab. 2020 May 5;31(5):1004-1016.e5. doi: 10.1016/j.cmet.2020.04.004. Cell Metab. 2020. PMID: 32375022 Free PMC article.

2

Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3.

Blum B, Hrvatin S, Schuetz C, Bonal C, Rezania A, Melton DA. Blum B, et al. Among authors: melton da. Nat Biotechnol. 2012 Feb 26;30(3):261-4. doi: 10.1038/nbt.2141. Nat Biotechnol. 2012. PMID: 22371083 Free PMC article.

3

Betatrophin: a hormone that controls pancreatic β cell proliferation.

Yi P, Park JS, Melton DA. Yi P, et al. Among authors: melton da. Cell. 2013 May 9;153(4):747-58. doi: 10.1016/j.cell.2013.04.008. Epub 2013 Apr 25. Cell. 2013. PMID: 23623304 Free PMC article. Retracted.

4

Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.

Blum B, Roose AN, Barrandon O, Maehr R, Arvanites AC, Davidow LS, Davis JC, Peterson QP, Rubin LL, Melton DA. Blum B, et al. Among authors: melton da. Elife. 2014 Sep 16;3:e02809. doi: 10.7554/eLife.02809. Elife. 2014. PMID: 25233132 Free PMC article.

5

Generation of functional human pancreatic β cells in vitro.

Pagliuca FW, Millman JR, Gürtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA. Pagliuca FW, et al. Among authors: melton da. Cell. 2014 Oct 9;159(2):428-39. doi: 10.1016/j.cell.2014.09.040. Cell. 2014. PMID: 25303535 Free PMC article.

6

Perspectives on the activities of ANGPTL8/betatrophin.

Yi P, Park JS, Melton DA. Yi P, et al. Among authors: melton da. Cell. 2014 Oct 23;159(3):467-8. doi: 10.1016/j.cell.2014.09.028. Cell. 2014. PMID: 25417096 Free article. No abstract available.

7

A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.

Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I. Baron M, et al. Among authors: melton da. Cell Syst. 2016 Oct 26;3(4):346-360.e4. doi: 10.1016/j.cels.2016.08.011. Epub 2016 Sep 22. Cell Syst. 2016. PMID: 27667365 Free PMC article.

8

Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas.

Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R. Ma H, et al. Among authors: melton da. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3924-3929. doi: 10.1073/pnas.1702059115. Epub 2018 Mar 29. Proc Natl Acad Sci U S A. 2018. PMID: 29599125 Free PMC article.

9

Apolipoprotein E is a pancreatic extracellular factor that maintains mature β-cell gene expression.

Mahmoud AI, Galdos FX, Dinan KA, Jedrychowski MP, Davis JC, Vujic A, Rachmin I, Shigley C, Pancoast JR, Lee S, Hollister-Lock J, MacGillivray CM, Gygi SP, Melton DA, Weir GC, Lee RT. Mahmoud AI, et al. Among authors: melton da. PLoS One. 2018 Oct 10;13(10):e0204595. doi: 10.1371/journal.pone.0204595. eCollection 2018. PLoS One. 2018. PMID: 30303984 Free PMC article.

10

YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells.

Rosado-Olivieri EA, Anderson K, Kenty JH, Melton DA. Rosado-Olivieri EA, et al. Among authors: melton da. Nat Commun. 2019 Apr 1;10(1):1464. doi: 10.1038/s41467-019-09404-6. Nat Commun. 2019. PMID: 30931946 Free PMC article.

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