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The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.
Griffett K, Bedia-Diaz G, Hegazy L, de Vera IMS, Wanninayake US, Billon C, Koelblen T, Wilhelm ML, Burris TP. Griffett K, et al. Among authors: koelblen t. Cell Chem Biol. 2020 Oct 15;27(10):1272-1284.e4. doi: 10.1016/j.chembiol.2020.07.013. Epub 2020 Aug 6. Cell Chem Biol. 2020. PMID: 32763139 Free article.
Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists.
Griffett K, Hayes M, Bedia-Diaz G, Appourchaux K, Sanders R, Boeckman MP, Koelblen T, Zhang J, Schulman IG, Elgendy B, Burris TP. Griffett K, et al. Among authors: koelblen t. ACS Chem Biol. 2022 May 20;17(5):1143-1154. doi: 10.1021/acschembio.2c00057. Epub 2022 Apr 13. ACS Chem Biol. 2022. PMID: 35417135
Progress toward the De Novo Asymmetric Synthesis of Euphanes.
Wai H, Koelblen T, Hayes ME, Burris TP, Micalizio GC. Wai H, et al. Among authors: koelblen t. Org Lett. 2022 May 27;24(20):3686-3690. doi: 10.1021/acs.orglett.2c01299. Epub 2022 May 18. Org Lett. 2022. PMID: 35584298 Free PMC article.
Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB.
Murray MH, Valfort AC, Koelblen T, Ronin C, Ciesielski F, Chatterjee A, Veerakanellore GB, Elgendy B, Walker JK, Hegazy L, Burris TP. Murray MH, et al. Among authors: koelblen t. Nat Commun. 2022 Nov 21;13(1):7131. doi: 10.1038/s41467-022-34892-4. Nat Commun. 2022. PMID: 36414641 Free PMC article.