Garcia-Ocaña A - Search Results

1

Nrf2: The Master and Captain of Beta Cell Fate.

Baumel-Alterzon S, Katz LS, Brill G, Garcia-Ocaña A, Scott DK. Baumel-Alterzon S, et al. Trends Endocrinol Metab. 2021 Jan;32(1):7-19. doi: 10.1016/j.tem.2020.11.002. Epub 2020 Nov 23. Trends Endocrinol Metab. 2021. PMID: 33243626 Free PMC article. Review.

2

Glucose infusion in mice: a new model to induce beta-cell replication.

Alonso LC, Yokoe T, Zhang P, Scott DK, Kim SK, O'Donnell CP, Garcia-Ocaña A. Alonso LC, et al. Diabetes. 2007 Jul;56(7):1792-801. doi: 10.2337/db06-1513. Epub 2007 Mar 30. Diabetes. 2007. PMID: 17400928 Free PMC article.

3

Parathyroid hormone-related protein enhances human ß-cell proliferation and function with associated induction of cyclin-dependent kinase 2 and cyclin E expression.

Guthalu Kondegowda N, Joshi-Gokhale S, Harb G, Williams K, Zhang XY, Takane KK, Zhang P, Scott DK, Stewart AF, Garcia-Ocaña A, Vasavada RC. Guthalu Kondegowda N, et al. Diabetes. 2010 Dec;59(12):3131-8. doi: 10.2337/db09-1796. Epub 2010 Sep 28. Diabetes. 2010. PMID: 20876711 Free PMC article.

4

Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.

Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC, Alonso LC, Garcia-Ocaña A. Velazquez-Garcia S, et al. Diabetes. 2011 Oct;60(10):2546-59. doi: 10.2337/db10-1783. Epub 2011 Sep 12. Diabetes. 2011. PMID: 21911744 Free PMC article.

5

ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.

Metukuri MR, Zhang P, Basantani MK, Chin C, Stamateris RE, Alonso LC, Takane KK, Gramignoli R, Strom SC, O'Doherty RM, Stewart AF, Vasavada RC, Garcia-Ocaña A, Scott DK. Metukuri MR, et al. Diabetes. 2012 Aug;61(8):2004-15. doi: 10.2337/db11-0802. Epub 2012 May 14. Diabetes. 2012. PMID: 22586588 Free PMC article.

6

Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.

Bernal-Mizrachi E, Kulkarni RN, Scott DK, Mauvais-Jarvis F, Stewart AF, Garcia-Ocaña A. Bernal-Mizrachi E, et al. Diabetes. 2014 Mar;63(3):819-31. doi: 10.2337/db13-1146. Diabetes. 2014. PMID: 24556859 Free PMC article. Review.

7

Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice.

Alvarez-Perez JC, Rosa TC, Casinelli GP, Valle SR, Lakshmipathi J, Rosselot C, Rausell-Palamos F, Vasavada RC, García-Ocaña A. Alvarez-Perez JC, et al. Mol Endocrinol. 2014 Dec;28(12):2038-48. doi: 10.1210/me.2014-1207. Mol Endocrinol. 2014. PMID: 25361392 Free PMC article.

8

Diabetes mellitus--advances and challenges in human β-cell proliferation.

Wang P, Fiaschi-Taesch NM, Vasavada RC, Scott DK, García-Ocaña A, Stewart AF. Wang P, et al. Nat Rev Endocrinol. 2015 Apr;11(4):201-12. doi: 10.1038/nrendo.2015.9. Epub 2015 Feb 17. Nat Rev Endocrinol. 2015. PMID: 25687999 Review.

9

Anti-incretin, Anti-proliferative Action of Dopamine on β-Cells.

Maffei A, Segal AM, Alvarez-Perez JC, Garcia-Ocaña A, Harris PE. Maffei A, et al. Mol Endocrinol. 2015 Apr;29(4):542-57. doi: 10.1210/me.2014-1273. Epub 2015 Mar 9. Mol Endocrinol. 2015. PMID: 25751312 Free PMC article.

10

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.

Wang P, Alvarez-Perez JC, Felsenfeld DP, Liu H, Sivendran S, Bender A, Kumar A, Sanchez R, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Nat Med. 2015 Apr;21(4):383-8. doi: 10.1038/nm.3820. Epub 2015 Mar 9. Nat Med. 2015. PMID: 25751815 Free PMC article.

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